BENHA UNIVERSITY, CREDIT HOURS SYSTEM
PHARMACOLOGY, REPRODUCTIVE SYSTEM (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
REPRODUCTIVE DRUGS (GONADOTROPINS)
MCQs
Notes:
(i) Each Question has 4 points to choose from. Choose ONLY ONE point to answer the Question.
(ii) Answer the questions after carefully reading the text.
1. The term “Gonadotropin” refers to:
A) A drug which is secreted from anterior pituitary and has affinity to act on gonads.
B) A drug which is secreted from posterior pituitary and has affinity to act on gonads.
C) A drug which acts on gonads increasing their vascularity and activity.
D) Both A & C may apply.
2. The term “GN-RH” refers to an agent that activates anterior pituitary to secrete gonadotropins, it is
physiologically secreted from hypothalamus & pharmacologically may be given as injection.
A) True.
B) False.
3. All tropic hormones are under the control of releasing factors, except luteotropin which is under an
inhibitory factor.
A) True.
B) False.
4. Gonadotropins and Gonadotropin releasing factors are all peptide in nature and, therefore, must be given
orally not parenterally.
A) True
B) False
5. Which of the following statements is true for gonadotropins?
A) Effective after oral administration.
B) Act via intracellular cytoplasmic receptors.
C) Can be used for oestrous synchronization.
D) Not controlled by feedback mechanisms.
6. The following features are associated with hCG as a gonadotropin, except:
A) Interacts with extracellular G-protein coupled receptor type.
B) Its main constituent is FSH that is responsible for puberty in male.
C) It is non-steroidal in nature and must be given parenterally.
D) It increases during pregnancy giving the basis of Friedman’s test.
7. All the following actions and uses are true regarding FSH, except:
A) Stimulates folliculogenesis in male and female.
B) Stimulates oestradiol synthesis in female.
C) Stimulates testosterone synthesis in male.
D) Useful in oestrous synchronization in female.
Reproductive system Pharmacology Surviving Revision
, BENHA UNIVERSITY, CREDIT HOURS SYSTEM
8. Urofollitropin is a gonadotropin preparation that consists of both FSH and LH?
A) True
B) False
9. Which of the following features is associated with Clomiphene as a reproductive drug:
A) It is a gonadotropin preparation that contains FSH.
B) It is a gonadotropin preparation that contains LH.
C) It is a gonadotropin preparation that contains FSH-LH-RF.
D) It is a preparation that enhances the release of FSH & LH by antagonizing oestrogens.
10. Gonadotropins mediate their actions on gonads via activating which of the following receptors:
A) Extracellular G-p coupled receptors.
B) Extracellular Enzyme-linked receptors.
C) Intracellular nuclear receptors.
D) Intracellular cytoplasmic receptors.
11. Which of the following features is associated with LH:
A) Stimulates folliculogenesis in male and female.
B) Stimulates oestradiol synthesis in female.
C) Stimulates testosterone synthesis in male.
D) Acts via intracellular nuclear receptors.
12. Gonadorelin is one of gonadotropin preparations that consists of FSH-LH-RH.
A) True
B) False
13. LH is responsible for synthesis and release of testosterone, and thus is useful in cryptorchidism.
A) True
B) False
14. Bromocriptine is a dopamine analogue that inhibits LT release, so could be used in treatment of agalactia.
A) True
B) False
15. Urofollitropin (Fertinorm) is preparation containing FSH mainly, hCG (Pregnyl) is a preparation containing LH
mainly, while Menotropin (Menopur) contains FSH-LH combination.
A) True
B) False
16. Placental but not Pituitary gonadotropins are the main source for gonadotropic pharmaceutical
preparations based on higher blood concentrations.
A) True
B) False
[End of questions; Total points = 16]
Reproductive system Pharmacology Surviving Revision
PHARMACOLOGY, REPRODUCTIVE SYSTEM (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
REPRODUCTIVE DRUGS (GONADOTROPINS)
MCQs
Notes:
(i) Each Question has 4 points to choose from. Choose ONLY ONE point to answer the Question.
(ii) Answer the questions after carefully reading the text.
1. The term “Gonadotropin” refers to:
A) A drug which is secreted from anterior pituitary and has affinity to act on gonads.
B) A drug which is secreted from posterior pituitary and has affinity to act on gonads.
C) A drug which acts on gonads increasing their vascularity and activity.
D) Both A & C may apply.
2. The term “GN-RH” refers to an agent that activates anterior pituitary to secrete gonadotropins, it is
physiologically secreted from hypothalamus & pharmacologically may be given as injection.
A) True.
B) False.
3. All tropic hormones are under the control of releasing factors, except luteotropin which is under an
inhibitory factor.
A) True.
B) False.
4. Gonadotropins and Gonadotropin releasing factors are all peptide in nature and, therefore, must be given
orally not parenterally.
A) True
B) False
5. Which of the following statements is true for gonadotropins?
A) Effective after oral administration.
B) Act via intracellular cytoplasmic receptors.
C) Can be used for oestrous synchronization.
D) Not controlled by feedback mechanisms.
6. The following features are associated with hCG as a gonadotropin, except:
A) Interacts with extracellular G-protein coupled receptor type.
B) Its main constituent is FSH that is responsible for puberty in male.
C) It is non-steroidal in nature and must be given parenterally.
D) It increases during pregnancy giving the basis of Friedman’s test.
7. All the following actions and uses are true regarding FSH, except:
A) Stimulates folliculogenesis in male and female.
B) Stimulates oestradiol synthesis in female.
C) Stimulates testosterone synthesis in male.
D) Useful in oestrous synchronization in female.
Reproductive system Pharmacology Surviving Revision
, BENHA UNIVERSITY, CREDIT HOURS SYSTEM
8. Urofollitropin is a gonadotropin preparation that consists of both FSH and LH?
A) True
B) False
9. Which of the following features is associated with Clomiphene as a reproductive drug:
A) It is a gonadotropin preparation that contains FSH.
B) It is a gonadotropin preparation that contains LH.
C) It is a gonadotropin preparation that contains FSH-LH-RF.
D) It is a preparation that enhances the release of FSH & LH by antagonizing oestrogens.
10. Gonadotropins mediate their actions on gonads via activating which of the following receptors:
A) Extracellular G-p coupled receptors.
B) Extracellular Enzyme-linked receptors.
C) Intracellular nuclear receptors.
D) Intracellular cytoplasmic receptors.
11. Which of the following features is associated with LH:
A) Stimulates folliculogenesis in male and female.
B) Stimulates oestradiol synthesis in female.
C) Stimulates testosterone synthesis in male.
D) Acts via intracellular nuclear receptors.
12. Gonadorelin is one of gonadotropin preparations that consists of FSH-LH-RH.
A) True
B) False
13. LH is responsible for synthesis and release of testosterone, and thus is useful in cryptorchidism.
A) True
B) False
14. Bromocriptine is a dopamine analogue that inhibits LT release, so could be used in treatment of agalactia.
A) True
B) False
15. Urofollitropin (Fertinorm) is preparation containing FSH mainly, hCG (Pregnyl) is a preparation containing LH
mainly, while Menotropin (Menopur) contains FSH-LH combination.
A) True
B) False
16. Placental but not Pituitary gonadotropins are the main source for gonadotropic pharmaceutical
preparations based on higher blood concentrations.
A) True
B) False
[End of questions; Total points = 16]
Reproductive system Pharmacology Surviving Revision
