BENHA UNIVERSITY, CREDIT HOURS SYSTEM
PHARMACOLOGY, DIGESTIVE SYSTEM (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
GIT DRUGS (Quiz + Answers)
Notes:
(i) Read the associated signs and diagnose the case.
(ii) Answer the questions after carefully reading the text.
A patient with complaints of severe persistent heartburn and an unpleasant acidic
taste in his mouth. The condition is likely to be GERD (gastroesophageal reflux
disease), which is the most appropriate drugs to deal with the condition?
A. Aluminium Hydroxide
B. Pantoprazole
C. Granisetron
D. Dicyclomine
The answer is (B).
It is appropriate to treat this condition with a proton-pump inhibitor (PPI) to
reduce acid production and promote healing.
AlOH3 is an antacid that would decrease gastric acid, but its effects are of
shorter duration when compared to those of the PPIs and H2 receptor antagonists
as well.
Dicyclomine is an antimuscarinic drug that is mainly used as an antispasmodic for
IBS via blocking of M3 cholinoceptor; parietal cells have M1 cholinoceptor type.
Granisetron is a 5-HT receptor antagonist, it is an antemetic, and not
appropriate for GERD.
Which medicament for gastrointestinal disorders is contraindicated in pregnancy?
Give your interpretation.
A. Calcium carbonate
B. Famotidine
C. Lansoprazole
D. Misoprostol
The answer is (D).
Misoprostol is a synthetic prostaglandin analogue that is contraindicated in
pregnancy as it has ecbolic action and may stimulate uterine contractions causing
abortion.
The other medications may be used safely during pregnancy for the treatment of
heartburn or peptic ulcer; Famotidine via blocking H2 receptor; Lansoprazole via
inhibiting Proton pump; and Carbonate chemically.
Digestive system Pharmacology Surviving Revision
PHARMACOLOGY, DIGESTIVE SYSTEM (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
GIT DRUGS (Quiz + Answers)
Notes:
(i) Read the associated signs and diagnose the case.
(ii) Answer the questions after carefully reading the text.
A patient with complaints of severe persistent heartburn and an unpleasant acidic
taste in his mouth. The condition is likely to be GERD (gastroesophageal reflux
disease), which is the most appropriate drugs to deal with the condition?
A. Aluminium Hydroxide
B. Pantoprazole
C. Granisetron
D. Dicyclomine
The answer is (B).
It is appropriate to treat this condition with a proton-pump inhibitor (PPI) to
reduce acid production and promote healing.
AlOH3 is an antacid that would decrease gastric acid, but its effects are of
shorter duration when compared to those of the PPIs and H2 receptor antagonists
as well.
Dicyclomine is an antimuscarinic drug that is mainly used as an antispasmodic for
IBS via blocking of M3 cholinoceptor; parietal cells have M1 cholinoceptor type.
Granisetron is a 5-HT receptor antagonist, it is an antemetic, and not
appropriate for GERD.
Which medicament for gastrointestinal disorders is contraindicated in pregnancy?
Give your interpretation.
A. Calcium carbonate
B. Famotidine
C. Lansoprazole
D. Misoprostol
The answer is (D).
Misoprostol is a synthetic prostaglandin analogue that is contraindicated in
pregnancy as it has ecbolic action and may stimulate uterine contractions causing
abortion.
The other medications may be used safely during pregnancy for the treatment of
heartburn or peptic ulcer; Famotidine via blocking H2 receptor; Lansoprazole via
inhibiting Proton pump; and Carbonate chemically.
Digestive system Pharmacology Surviving Revision
