BENHA UNIVERSITY, CREDIT HOURS SYSTEM
PHARMACOLOGY, CARDIOVASCULAR SYSTEM (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
CARDIOVASCULAR DRUGS (Quiz 2 + Answers)
Notes:
(i) Read the associated signs and diagnose the case.
(ii) Answer the questions after carefully reading the text.
A patient has started on therapy for hypertension and since then a state of
persistent, dry cough has been developed. Which one among the following
antihypertensives is most likely responsible for this side effect?
A) Atenolol
B) Lisinopril
C) Losartan
D) Nifedipine
The answer is (B).
Persistent cough is an adverse effect of the use of ACE Inhibitors such as
Lisinopril.
Losartan is an Angiotensin receptor blocker that has the same beneficial effects
as the ACE inhibitor Lisinopril but is less likely to produce such a cough.
Atenolol and Nifedipine do not cause this side effect.
Cough could be a result of increasing Kinins such as Substance P and Tachykinin
due to inhibition of Kininase.
A patient with resistant hypertension. Which diuretic is hoped to improve blood
pressure that resisted other antihypertensives including thiazides?
Hypertension that resisted more than an antihypertensive medication, without
reaching the targeted blood pressure, often responds well to the group of
aldosterone antagonists as Spironolactone (Aldactone).
Cardiovascular system Pharmacology Surviving Revision
PHARMACOLOGY, CARDIOVASCULAR SYSTEM (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
CARDIOVASCULAR DRUGS (Quiz 2 + Answers)
Notes:
(i) Read the associated signs and diagnose the case.
(ii) Answer the questions after carefully reading the text.
A patient has started on therapy for hypertension and since then a state of
persistent, dry cough has been developed. Which one among the following
antihypertensives is most likely responsible for this side effect?
A) Atenolol
B) Lisinopril
C) Losartan
D) Nifedipine
The answer is (B).
Persistent cough is an adverse effect of the use of ACE Inhibitors such as
Lisinopril.
Losartan is an Angiotensin receptor blocker that has the same beneficial effects
as the ACE inhibitor Lisinopril but is less likely to produce such a cough.
Atenolol and Nifedipine do not cause this side effect.
Cough could be a result of increasing Kinins such as Substance P and Tachykinin
due to inhibition of Kininase.
A patient with resistant hypertension. Which diuretic is hoped to improve blood
pressure that resisted other antihypertensives including thiazides?
Hypertension that resisted more than an antihypertensive medication, without
reaching the targeted blood pressure, often responds well to the group of
aldosterone antagonists as Spironolactone (Aldactone).
Cardiovascular system Pharmacology Surviving Revision
