Integrated Exam 1 Practice Questions and

Integrated Exam 1 Practice Questions and Answers Latest 2022/2023 (All correct answers are indicated on top of every question) B.) Ingestion The most common route of accidental exposure to toxicants in toddlers is: A.) Inhalation B.) Ingestion C.) Contact (skin, etc.) D.) Puncture wounds E.) Other E.) a and c Forensic toxicology requires the participation of: A.) Poison control center B.) Emergency personnel C.) Crime lab D.) a and b E.) a and c E.) c and d Toxicogenetics may explain: A.) The response of population groups to major toxicants B.) The cellular response to the toxicant C.) Idiosyncratic reactions D.) The development of individualized therapies E.) c and d E.) b and d A toxicant that is inhaled: A.) Will never get in the bloodstream B.) Can be stored in the liver C.) Is exclusively eliminated by the lungs D.) Can be eliminated by the kidneys E.) b and d D.) a and b Intoxications in the elderly can be worsened by: A.) Irregular eating habits B.) Impaired kidney function C.) Undeveloped blood-brain barrier D.) a and b E.) All of the above B.) A synergistic effect A drug combination whose toxic effect can be described as (5+5=30) refers to: A.) Potentiation B.) A synergistic effect C.) An additive effect D.) a and b E.) a and c D.) When two chemicals counterbalance each others effect in the same physiologic function Functional antagonism describes: A.) The interaction of two substances that react generating an inactive product B.) The prevention of the absorption of a compound by another C.) Increased metabolism of the toxic compound induced by another compound D.) When two chemicals counterbalance each others effect in the same physiologic function E.) When a chemical blocks the binding of another to its receptor D.) a and b The quantal response: A.) Is by definition an all or non response B.) Has a bell-shaped curve C.) Is linear through a dose range D.) a and b E.) a and c E.) b and c The curve describing the response to essential nutrients: A.) Is sigmoidal B.) Is U-shaped C.) Is also called hormesis D.) Is shaped as a bell E.) b and c A.) Have the same efficacy Two drugs that have the same ED50: A.) Have the same efficacy B.) Have the same potency C.) Will have the same therapeutic index D.) Will have the same margin of safety E.) None of the above C.) Is irreversible Damage to the CNS: A.) Can be reversible B.) Always leads to cancer C.) Is irreversible D.) a and b E.) b and c C.) Chronic exposire to benzene A delayed toxicity can include: A.) Corrosive damage to the esophagus