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1). Hives (urticaria) are an example of a:
Ans: Type 1 hypersensitivity reaction.
2). Anaphylaxis is what type of reaction?
Ans: type 1 hypersensitivity
3). Which of the following are considered the "first responders" of the innate immune system?
Ans: neutrophils
4). Allergic contact dermatitis is an example of what type of
hypersensitivity reaction.
Ans: type 4 hypersensitivity reaction
5). Type 2 (cytotoxic) hypersensitivity reactions are mediated by:
Ans: IgG or IgM
6). Type 1 hypersensitivity reaction is mediated by
Ans: IgE
7). Allergic asthma is an example of
Ans: type 1 hypersensitivity reaction
8). Type 2 hypersensitivity
Ans: tissue specific
Primary effector cells of type 2
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, 9).
Ans: macrophages
10). Examples of type 2 reactions
Ans: drug allergies, hemolytic anemia, blood transfusion mismatch, allergies against
infectious agents
11). Type 2 causes
Ans: The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
12). Type 3 hypersensitivity reaction
Ans: antigen-antibody response
13). Where does the antibody bind to the antigen in type 3 response?
Ans: in blood or body fluids and then circulates to tissue
14). Where does the antibody bind to the antigen in type 1, 2, and 4?
Ans: on cell surface
15). Primary effector cell in type 3
Ans: neutrophils
16). Example of type 3 reaction
Ans: serum sickness
17). Type 4 hypersensitivity reaction
Ans: cell-mediated response
Primary mediators of type 4
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, 18).
Ans: lymphocytes and macrophages
19). Type 4 mediated by
Ans: T lymphocytes and do not use antibodies
20). Example of type 4
Ans: localized contact dermatitis (poison ivy)
21). Damage occurs with abo incompatibility because:
Ans: Complement damages RBC membrane causing cell lysis.
22). Which of the following is the underlying pathology for hay fever?
Ans: mast cell degranulation
23). The diagnosis for an individual who presents to the office with sudden swollen lips and
eyes, shortness of breath and throat tightness after a bee sting is:
Ans: anaphylaxis
24). Which of the following assessment findings would be expected in a patient who presents
with urticaria?
Ans: Eosinophilia.
25). An example of a primary immunodeficiency is:
Ans: Chronic Granulomatous Disease.
26). What is a predominant cause of secondary immune deficiencies worldwide.
Ans: Malnutrition
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