NURS 660 EXAM 2
1. Which medication has the SE of losing hair: Lithium
2. The pt is bipolar, and had a partial response to depakote and
now is going to be augmented with an atypical antipsychotic,
the effects of atypical antipsychotics in non-psychotic mania
may be due to what: indirect effect on glutamate release via 5H2A
antagonism
3. A pt has had some success with his current
antidepression medication, has tried many different
antidepressants, so you decide to augment with
L-methyl-folate. What is the hypothesis behind L methyl Folate
boosting the therapeutic efficacy of antidepressants...what is
the MOA?: boosts monamine neurotransmitter function in bipolar
disorder
4. You have a pt that has been very depressed and has
insomnia problems with concentrations, weight loss and SI.
You start them on an AD and his symptoms have abated,
however which of the following symptoms is the most likely to
1/4
, be residual following the successful tx of other symptoms?: -
insomnia
5. Which class of antidepressant have a lower incidence of
sexual SE? What medication is used in the tx of BP/mania and
is used in prophylaxis as well as antidepressant
augmentation? Which medication is this?: Wellbutrin
6. What medication is a very potent CYP450 inhibitor and can
dangerously elevate lamotrigine?: Valproate
7. Which class of antidepressant has the worst discontinuation
syndrome?-
: Cymbalta
8. You have a female pt complaining of lactating and is not
pregnant w/
no children. She has been taking risperidone. Which medication
would you avoid if you were to switch her to another med?":
Paliperidone
9. A pt is on Prozac and it has stopped working. Patient has
been on many other antidepressants and wants to try an MAOI
2/4
1. Which medication has the SE of losing hair: Lithium
2. The pt is bipolar, and had a partial response to depakote and
now is going to be augmented with an atypical antipsychotic,
the effects of atypical antipsychotics in non-psychotic mania
may be due to what: indirect effect on glutamate release via 5H2A
antagonism
3. A pt has had some success with his current
antidepression medication, has tried many different
antidepressants, so you decide to augment with
L-methyl-folate. What is the hypothesis behind L methyl Folate
boosting the therapeutic efficacy of antidepressants...what is
the MOA?: boosts monamine neurotransmitter function in bipolar
disorder
4. You have a pt that has been very depressed and has
insomnia problems with concentrations, weight loss and SI.
You start them on an AD and his symptoms have abated,
however which of the following symptoms is the most likely to
1/4
, be residual following the successful tx of other symptoms?: -
insomnia
5. Which class of antidepressant have a lower incidence of
sexual SE? What medication is used in the tx of BP/mania and
is used in prophylaxis as well as antidepressant
augmentation? Which medication is this?: Wellbutrin
6. What medication is a very potent CYP450 inhibitor and can
dangerously elevate lamotrigine?: Valproate
7. Which class of antidepressant has the worst discontinuation
syndrome?-
: Cymbalta
8. You have a female pt complaining of lactating and is not
pregnant w/
no children. She has been taking risperidone. Which medication
would you avoid if you were to switch her to another med?":
Paliperidone
9. A pt is on Prozac and it has stopped working. Patient has
been on many other antidepressants and wants to try an MAOI
2/4
