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The presentation is about hyper sensitivity and its types

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Immunopathology Unit
Department of Pathology
College of Medicine &
Medical City
King Saud University

, Reference
Kuby Immunology 8th Edition
Chapter 15

, Objectives
• To know that hypersensitivity reactions are over and excessive
immune responses that can be harmful to body in four different
ways

• To be familiar with inflammatory processes in Type I
hypersensitivity reaction that mediates allergic inflammation

• To recognize that Type II hypersensitivity deals with immune
responses against antigens that are integral part of cell membrane
and are usually associated with autoimmune disorders

• To know that Type III hypersensitivity reactions are mediated by
immune complexes and cause vasculitis

• To describe Type IV hypersensitivity is a purely cell mediated
immune response associated with chronic inflammation

, What is hypersensitivity?

• Protective immunity: desirable reaction

• Hypersensitivity: undesirable reaction

• Undesirable responses can be mediated by
– Antibody binding to antigens (Types I-III)
– Cell mediated reaction to chemicals or proteins
(Type IV)

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