Midterm Exam: NR565/ NR 565 Advanced
Pharmacology Care
1). Ascvd risk score
Ans: Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5%
2). Ezetimibe use
Ans: Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with
a statin or fibrate
3). Ezetimibe
Ans: Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides
4). Lifestyle changes for high cholesterol
Ans: Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation
5). Minimizing side effects
Ans: Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects
6). Organic nitrates therapeutic action
Ans: Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation
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, 7). Ranolazine contraindications
Ans: Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal
drugs, and some CCB
8). Statin prescription age
Ans: Avoid in children under 10
9). Ccb role in variant angina
Ans: Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply
10). Hf worsening symptoms medication
Ans: Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms
11). Ccb stable angina
Ans: Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand
12). Nitro patches side effect response
Ans: Prescribe a BB to help with increased heart rate
13). Cyp450 inhibitors and reducers
Ans: When not used correctly, they lead to increased side effects, adverse reactions,
and toxicity
14). Gouty arthritis treatment decision
Ans: In patients with infrequent flareups (less than three per year), NSAIDs are the first
line agent for relieving pain
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Pharmacology Care
1). Ascvd risk score
Ans: Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5%
2). Ezetimibe use
Ans: Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with
a statin or fibrate
3). Ezetimibe
Ans: Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing
absorption from the small intestine, without affecting triglycerides
4). Lifestyle changes for high cholesterol
Ans: Non-drug measures to lower LDL, including diet, exercise, weight control, and
smoking cessation
5). Minimizing side effects
Ans: Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally
well-tolerated side effects
6). Organic nitrates therapeutic action
Ans: Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation
PaperStoc.com Page 1 of 11
, 7). Ranolazine contraindications
Ans: Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal
drugs, and some CCB
8). Statin prescription age
Ans: Avoid in children under 10
9). Ccb role in variant angina
Ans: Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply
10). Hf worsening symptoms medication
Ans: Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help
with symptoms
11). Ccb stable angina
Ans: Promotes relaxation of peripheral arterioles, decreasing afterload and reducing
cardiac oxygen demand
12). Nitro patches side effect response
Ans: Prescribe a BB to help with increased heart rate
13). Cyp450 inhibitors and reducers
Ans: When not used correctly, they lead to increased side effects, adverse reactions,
and toxicity
14). Gouty arthritis treatment decision
Ans: In patients with infrequent flareups (less than three per year), NSAIDs are the first
line agent for relieving pain
PaperStoc.com Page 2 of 11
