Midterm Exam: NR 567 / NR567 Advanced
Pharmacology for the AGACNP Exam Review |
Weeks 1- 4 Covered| Questions and Verified
Answers (2023/ 2024 Update)
1). Warfarin
Ans: Inhibits vitamin K activation of clotting factors II (prothrombin), VII, IX, and X
formed in the liver.
2). Promtamine sulfate
Ans: Heparin antidote
3). Vitamin k and fresh frozen plasma
Ans: warfarin antidote
4). Vitals, hematology, pt, inr, ptt
Ans: What assessments are to be performed on a patient using anticoagulants?
5). Ptt
Ans: normal = 20-35 seconds; on heparin therapy goal is 1.5 - 2.5 times this
6). 2-3
Ans: INR goal for warfarin therapy?
7). Pt
Ans: Normal range is 11-13.5 secs.
8). Aspirin
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, Ans: Common anti-platelet drug that can be purchased over the counter, used in
patients
9). Clopidogrel
Ans: anti-platelet used to reduce risk of stroke in patients with history of MI, CAD,
stents, bypass.
10). Ticlopidine
Ans: Anti-platelet drug reserved for patients allergic to aspirin; inhibits the binding of
fibrinogen to platelets during the first stage of the clotting cascade. Used in patients that
have already had thrombotic stroke.
11). Dipyridamole
Ans: • Inhibits cyclic nucleotide phosphodiesterase and reuptake of adenosine, both
actions result in reduced platelet aggregation and reactivity.
12). Heparin
Ans: First-line anticoagulant used for STEMI; administered with ASA, clopidogrel, and
a statin
13). Enoxaparin
Ans: may be used if the patient is not being referred for percutaneous coronary
intervention, during an MI
14). Morphine
Ans: Alleviates pain not relieved with nitrates
Produces mild vasodilation
15). Atorvastatin 80 mg loading dose, then daily.
Ans: Statin that is given during MI and the dose
16). Beta blocker
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, Ans: oral ______ ________ therapy within 24 hours of cardiac event unless
contraindicated
17). Calcium channel blockers
Ans: If beta-blockers are not tolerated, consider
18). Verapamil and dilatiazem
Ans: Examples of calcium channel blockers
19). 162-325 mg
Ans: Aspirin loading dose for an NSTEMI
20). 600 mg, 75mg daily
Ans: Loading dose of PLAVIX
21). Eptifibatide
Ans: Indicated for Acute coronary syndrome and used in combination with heparin,
aspirin, ticlid and plavix; adverse reactions: bleeding, hypotension, thrombocytopenia,
acute toxicity: decreased muscle tone, dyspnea, loss of righting reflex; baseline PT/aPTT,
H&H, platelet count ad monitor; watch for bleeding; quickly reversible so emergency
procedures may still be performed shortly after discontinuing infusion
22). Tirofiban
Ans: Glycoprotein IIb/IIIa inhibitor used for high risk patients with planned PCTA
23). Aces and arbs
Ans: Reduces cardiac remodeling post-MI, Improves patient survival in those with
heart failure or anterior myocardial infarction
24). Reteplase
PaperStoc.com Page 3 of 22
Pharmacology for the AGACNP Exam Review |
Weeks 1- 4 Covered| Questions and Verified
Answers (2023/ 2024 Update)
1). Warfarin
Ans: Inhibits vitamin K activation of clotting factors II (prothrombin), VII, IX, and X
formed in the liver.
2). Promtamine sulfate
Ans: Heparin antidote
3). Vitamin k and fresh frozen plasma
Ans: warfarin antidote
4). Vitals, hematology, pt, inr, ptt
Ans: What assessments are to be performed on a patient using anticoagulants?
5). Ptt
Ans: normal = 20-35 seconds; on heparin therapy goal is 1.5 - 2.5 times this
6). 2-3
Ans: INR goal for warfarin therapy?
7). Pt
Ans: Normal range is 11-13.5 secs.
8). Aspirin
PaperStoc.com Page 1 of 22
, Ans: Common anti-platelet drug that can be purchased over the counter, used in
patients
9). Clopidogrel
Ans: anti-platelet used to reduce risk of stroke in patients with history of MI, CAD,
stents, bypass.
10). Ticlopidine
Ans: Anti-platelet drug reserved for patients allergic to aspirin; inhibits the binding of
fibrinogen to platelets during the first stage of the clotting cascade. Used in patients that
have already had thrombotic stroke.
11). Dipyridamole
Ans: • Inhibits cyclic nucleotide phosphodiesterase and reuptake of adenosine, both
actions result in reduced platelet aggregation and reactivity.
12). Heparin
Ans: First-line anticoagulant used for STEMI; administered with ASA, clopidogrel, and
a statin
13). Enoxaparin
Ans: may be used if the patient is not being referred for percutaneous coronary
intervention, during an MI
14). Morphine
Ans: Alleviates pain not relieved with nitrates
Produces mild vasodilation
15). Atorvastatin 80 mg loading dose, then daily.
Ans: Statin that is given during MI and the dose
16). Beta blocker
PaperStoc.com Page 2 of 22
, Ans: oral ______ ________ therapy within 24 hours of cardiac event unless
contraindicated
17). Calcium channel blockers
Ans: If beta-blockers are not tolerated, consider
18). Verapamil and dilatiazem
Ans: Examples of calcium channel blockers
19). 162-325 mg
Ans: Aspirin loading dose for an NSTEMI
20). 600 mg, 75mg daily
Ans: Loading dose of PLAVIX
21). Eptifibatide
Ans: Indicated for Acute coronary syndrome and used in combination with heparin,
aspirin, ticlid and plavix; adverse reactions: bleeding, hypotension, thrombocytopenia,
acute toxicity: decreased muscle tone, dyspnea, loss of righting reflex; baseline PT/aPTT,
H&H, platelet count ad monitor; watch for bleeding; quickly reversible so emergency
procedures may still be performed shortly after discontinuing infusion
22). Tirofiban
Ans: Glycoprotein IIb/IIIa inhibitor used for high risk patients with planned PCTA
23). Aces and arbs
Ans: Reduces cardiac remodeling post-MI, Improves patient survival in those with
heart failure or anterior myocardial infarction
24). Reteplase
PaperStoc.com Page 3 of 22
