UNE Biochem 1005 Final Study Set Questions With Complete Solutions.

UNE Biochem 1005 Final Study Set Questions With Complete Solutions. Which of the following best describes the structure of heme? -a nicotinamide structure that is readily oxidized -a negatively charged phosphate group -a planar porphyrin ring that binds iron -an n-link glycosylation A planar porphyrin ring that binds iron Covalent catalysis is used by many enzymes to cleave peptide bonds. Which of the following amino acids would not facilitate this type of catalysis? -valine -cysteine -serine -histidine Valine Which of the following proteins is likely to have quaternary structure? -a protein that contains both a-helix and b-sheet secondary structures -a multimeric protein that contains multiple peptide chains -a large transmembrane protein with seven a-helical domains -a small protein consisting of a single amino acid chain A multimeric protein that contains multiple peptide chains Which of the following amino acids would not be commonly found in the middle of an a-helix? -valine -leucine -tryptophan -proline Proline Both myglobin and hemoglobin contain heme. Myoglobin contains ___ heme rings. Hemoglobin contains ___ heme rings -1,4 -1,1 -4,1 -4,4 1 and 4 Which of the following best describes protein domain? -a linker region between two a-helical structures -any location on a protein that has a disulfide bond -a relatively large pattern of three-dimensional structure that is recognized across many proteins -a small grouping of secondary structures A relatively large pattern of 3D structure that is recognized across many proteins In the R state, all 4 subunits of hemoglobin exhibit a ___ affinity for oxygen. In the T state, all 4 subunits exhibit a ___ affinity for oxygen -High, low -High, high -Low, low -Low, high High, low Myoglobin is a ___ protein. Hemoglobin is a ____ protein -monomeric, tetrameric -monomeric, monomeric -tetrameric, tetrameric -tetrameric, monomeric -monomeric, tetrameric Dephosphorylation by a phosphatase requires all of the following except: -ATP -Water -Mg2+ ATP Competitive inhibitors typically resemble ___ -Active sites -Substrates -Cofactors -Enzymes Substrates During noncompetitive inhibition, Vmax is ____ -Decreased -Increased -Unchanged -Saturated Decreased During noncompetitive inhibition, KM is ____ -unchanged -decreased -increased -saturated Unchanged During competitive inhibition, Vmax is _____ -Increased -Decreased -Unchanged -Saturated Unchanged In the Michaelis-Menten equation, velocity (vi) and the Michaelis constant (Km) are ____ related -Equally -Directly -Inversely -Proportionally Inversely A decrease in histone acetylation will have which of the following impacts on the association of DNA and histones? -Increase DNA: histone association -Decrease DNA: histone association -Have no impact on the association of DNA and histones Increase DNA: histone association If a mutation is made within the active site of an enzyme resulting in an increase in Km, which of the following will be true with respect to the enzyme kinetics? -The enzyme will require a lower substrate concentration to reach 1/2Vmax -The enzyme will require a higher substrate concentration to reach 1/2Vmax -The concentration of the substrate needed to reach 1/2Vmax will not change -The Vmax of the reaction will increase The enzyme will require a higher substrate concentration to reach 1/2Vmax In the ETC which of the following compounds is the terminal electron acceptor? -H20 -FAD -NAD+ -O2 O2 In the malate aspartate shuttle, cytosolic oxaloacetate is ____ to form _____ as a means of moving reducing equivalents across the mitochondrial membrane -oxidized, malate -reduced, NADH -reduced, malate -oxidized, NADH Reduced, malate The fully reduced quinol form of Coq contains which of the following combinations of electrons and protons? -one electron and two protons -two electrons and two protons -one electron and one proton -two electrons and one proton Two electrons and two protons Dinitrophenol is an uncoupler of the electron transport chain. What impact does it have on the cell? -decrease O2 consumption, increase NADH, increase ATP -increase O2 consumption, increase NADH oxidation, decrease ATP -increase O2 consumption, decrease NADH oxidation, decrease ATP -increase ATP, decrease NADH, Increase ATP Increase O2 consumption Increase NADH oxidation Decrease ATP production Which is oxidized in the Q cycle? -Q- (semiquinone)