Pediatrics 01 Aquifer Questions And Answers
What is the effect of alkylating agents on feto?
Absence of digits, multiple anomalies.
What is the effect of aminoglycosides on feto?
Ototoxicity
What is the effect of antiepileptic drugs on feto?
Neural tube defects, cardiac defects, cleft palate, skeletal abnormalities (eg,
phalanx/nail hypoplasia, facial dysmorphism).
What is the effect of fluoroquinolones on feto?
Cartilage damage.
What is the effect of folate antagonists on feto?
Neural tube defects.
What is the effect of isotretinoin on feto?
Multiple severe birth defects.
What is the effect of lithium on feto?
Ebstein anomaly.
What is the effect of methimazole on feto?
Aplasia cutis congenita (congenital absence of skin, particularly on scalp).
What is the effect of tetracyclines on feto?
Discolored teeth, inhibited bone growth.
What is the effect of thalidomine on feto?
Limb defects (phocomelia, micromelia— "flipper" limbs).
What is the effect of warfarin on feto?
Bone and cartilage deformities (stippled epiphyses, nasal and limb hypoplasia), optic
nerve atrophy, fetal cerebral hemorrhage.
What is the effect of alcohol on feto?
Fetal alcohol syndrome
What is the effect of cocaine on feto?
Low birth weight, preterm birth, IUGR, placental abruption.
What is the effect of smoking on feto?
Low birth weight (leading cause in developed countries), preterm labor, placental
problems, IUGR, SIDS, ADHD.
What is the effect of iodine on feto?
Congenital goiter or hypothyroidism (cretinism).
What is the effect of maternal diabetes on feto?
Caudal regression syndrome, cardiac defects (eg, VSD), neural tube defects,
macrosomia, neonatal hypoglycemia (due to islet cell hyperplasia), polycythemia.
What is the effect of methylmercury on feto?
Neurotoxicity - Highest in swordfish, shark, tilefish, king mackerel.
What is the effect of vitamin A excess on feto?
Extremely high risk for spontaneous abortions and birth defects (cleft palate, cardiac).
What is the effect of X rays on feto?
Microcephaly and intellectual disability
What are the effects of ACE i on feto?
Renal failure, oligohydramnios, hypocalvaria.
What is the effect of alkylating agents on feto?
Absence of digits, multiple anomalies.
What is the effect of aminoglycosides on feto?
Ototoxicity
What is the effect of antiepileptic drugs on feto?
Neural tube defects, cardiac defects, cleft palate, skeletal abnormalities (eg,
phalanx/nail hypoplasia, facial dysmorphism).
What is the effect of fluoroquinolones on feto?
Cartilage damage.
What is the effect of folate antagonists on feto?
Neural tube defects.
What is the effect of isotretinoin on feto?
Multiple severe birth defects.
What is the effect of lithium on feto?
Ebstein anomaly.
What is the effect of methimazole on feto?
Aplasia cutis congenita (congenital absence of skin, particularly on scalp).
What is the effect of tetracyclines on feto?
Discolored teeth, inhibited bone growth.
What is the effect of thalidomine on feto?
Limb defects (phocomelia, micromelia— "flipper" limbs).
What is the effect of warfarin on feto?
Bone and cartilage deformities (stippled epiphyses, nasal and limb hypoplasia), optic
nerve atrophy, fetal cerebral hemorrhage.
What is the effect of alcohol on feto?
Fetal alcohol syndrome
What is the effect of cocaine on feto?
Low birth weight, preterm birth, IUGR, placental abruption.
What is the effect of smoking on feto?
Low birth weight (leading cause in developed countries), preterm labor, placental
problems, IUGR, SIDS, ADHD.
What is the effect of iodine on feto?
Congenital goiter or hypothyroidism (cretinism).
What is the effect of maternal diabetes on feto?
Caudal regression syndrome, cardiac defects (eg, VSD), neural tube defects,
macrosomia, neonatal hypoglycemia (due to islet cell hyperplasia), polycythemia.
What is the effect of methylmercury on feto?
Neurotoxicity - Highest in swordfish, shark, tilefish, king mackerel.
What is the effect of vitamin A excess on feto?
Extremely high risk for spontaneous abortions and birth defects (cleft palate, cardiac).
What is the effect of X rays on feto?
Microcephaly and intellectual disability
What are the effects of ACE i on feto?
Renal failure, oligohydramnios, hypocalvaria.
