NIH Stroke Scale – All Test Groups A-F
The nurse is obtaining consent from a subject newly recruited for a
clinical drug trial that will last for 6 months. All subjects will be given
gift certificates for participating. One subject says, "Well, I guess if the
drug doesn't work, I'll just have to put up with the symptoms for 6
months." What will the nurse tell the subject?
a. "Participation for the duration of the study is required."
b. "Participation may end at any time without penalty."
c. "Withdrawal from the study may end at any time, but the gift
certificate will not be given."
d. "You can request placement in the treatment group." - Answer
"Participation may end at any time without penalty."
The nurse is assisting with a clinical drug trial in which the side effects
of two effective drugs are being compared. A patient who would
benefit from either drug has elected to withdraw from the study, and
the nurse assists with the paperwork to facilitate this. This is an
example of
a. autonomy.
b. beneficence.
,NIH Stroke Scale – All Test Groups A-F
c. justice.
d. veracity - Answer autonomy
During a clinical drug trial for a new medication, researchers note a
previously unknown serious adverse effect occurring in more than 50%
of subjects. The study is discontinued. Which ethical principle is being
exercised?
a. Beneficence
b. Justice
c. Respect for persons
d. Veracity - Answer Beneficence
In a 5-year experimental clinical trial to investigate a new cancer
treatment, researchers in the second year note overwhelming
improvement in almost all of the subjects in the treatment group. The
lead researcher elects to continue the study. Which ethical principle is
being violated?
a. Beneficence
b. Justice
,NIH Stroke Scale – All Test Groups A-F
c. Respect for persons
d. Veracity - Answer Justice
The nurse is enrolling subjects for a double-blind experimental study.
One patient asks the nurse to explain the role of the experimental
group. The nurse will explain that subjects in the experimental group in
this type of study
a. are selected for participation in that group.
b. have unique baseline characteristics.
c. receive a placebo.
d. receive the treatment being evaluated. - Answer receive the
treatment being evaluated
The nurse is obtaining signatures on consent forms for participation in a
clinical drug trial. One patient says, "I'm not sure I want to do this, but I
need the cash." The nurse will take which action?
a. Ask the patient to clarify concerns.
b. Reinforce that cash is given to all subjects equally.
, NIH Stroke Scale – All Test Groups A-F
c. Report this statement to the party named on the consent.
d. Review the elements of the study and obtain consent. - Answer
Report this statement to the party named on the consent
Which is the characteristic of preclinical in vivo testing?
a. A comparison of experimental and control data in animals
b. A study conducted in a test tube in a laboratory
c. A study that determines the effects of the placebo in human
participants
d. A study to assess the seriousness of the disease to be treated -
Answer A comparison of experimental and control data in animals
Many drugs marketed in the 1980s may not be effective in a majority of
the population. The nurse understands that this is because these drugs
a. did not pass through the appropriate phases of clinical trials.
b. did not require human subject protections and are invalid.
c. were not tested on women, minorities, or children.
The nurse is obtaining consent from a subject newly recruited for a
clinical drug trial that will last for 6 months. All subjects will be given
gift certificates for participating. One subject says, "Well, I guess if the
drug doesn't work, I'll just have to put up with the symptoms for 6
months." What will the nurse tell the subject?
a. "Participation for the duration of the study is required."
b. "Participation may end at any time without penalty."
c. "Withdrawal from the study may end at any time, but the gift
certificate will not be given."
d. "You can request placement in the treatment group." - Answer
"Participation may end at any time without penalty."
The nurse is assisting with a clinical drug trial in which the side effects
of two effective drugs are being compared. A patient who would
benefit from either drug has elected to withdraw from the study, and
the nurse assists with the paperwork to facilitate this. This is an
example of
a. autonomy.
b. beneficence.
,NIH Stroke Scale – All Test Groups A-F
c. justice.
d. veracity - Answer autonomy
During a clinical drug trial for a new medication, researchers note a
previously unknown serious adverse effect occurring in more than 50%
of subjects. The study is discontinued. Which ethical principle is being
exercised?
a. Beneficence
b. Justice
c. Respect for persons
d. Veracity - Answer Beneficence
In a 5-year experimental clinical trial to investigate a new cancer
treatment, researchers in the second year note overwhelming
improvement in almost all of the subjects in the treatment group. The
lead researcher elects to continue the study. Which ethical principle is
being violated?
a. Beneficence
b. Justice
,NIH Stroke Scale – All Test Groups A-F
c. Respect for persons
d. Veracity - Answer Justice
The nurse is enrolling subjects for a double-blind experimental study.
One patient asks the nurse to explain the role of the experimental
group. The nurse will explain that subjects in the experimental group in
this type of study
a. are selected for participation in that group.
b. have unique baseline characteristics.
c. receive a placebo.
d. receive the treatment being evaluated. - Answer receive the
treatment being evaluated
The nurse is obtaining signatures on consent forms for participation in a
clinical drug trial. One patient says, "I'm not sure I want to do this, but I
need the cash." The nurse will take which action?
a. Ask the patient to clarify concerns.
b. Reinforce that cash is given to all subjects equally.
, NIH Stroke Scale – All Test Groups A-F
c. Report this statement to the party named on the consent.
d. Review the elements of the study and obtain consent. - Answer
Report this statement to the party named on the consent
Which is the characteristic of preclinical in vivo testing?
a. A comparison of experimental and control data in animals
b. A study conducted in a test tube in a laboratory
c. A study that determines the effects of the placebo in human
participants
d. A study to assess the seriousness of the disease to be treated -
Answer A comparison of experimental and control data in animals
Many drugs marketed in the 1980s may not be effective in a majority of
the population. The nurse understands that this is because these drugs
a. did not pass through the appropriate phases of clinical trials.
b. did not require human subject protections and are invalid.
c. were not tested on women, minorities, or children.
