Advanced Pharmacology

Advanced Pharmacology Explain Pharmacokinetics - correct answer - The study of how drugs are moved through the body and are encompassed in mechanisms of: Absorption Distribution Metabolism Excretion Think Kinetic (movement) Pharmacodynamics - correct answer - study of the biochemical and physiologic effects of drugs on the body Think Dynamic (change) majority of drugs either (a) mimic or inhibit normal physiological/biochemical processes or inhibit pathological processes in animals or (b) inhibit vital processes of endo- or ectoparasites and microbial organisms Summarize the main drug actions - correct answer - 1 - stimulating action through direct receptor agonism and downstream effects 2 - depressing action through direct receptor agonism and downstream effects (ex.: inverse agonist) 3- blocking/antagonizing action (as with silent antagonists), the drug binds the receptor but does not activate it 4- stabilizing action, the drug seems to act neither as a stimulant or as a depressant 5- exchanging/replacing substances or accumulating them to form a reserve (ex.: glycogen storage)