PCOL 824 Final Exam Questions with Answers All Correct

PCOL 824 Final Exam Questions with Answers All Correct serotonin receptor (5HT2C) - Answer-serotonin binding activates the satiety pathway leptin - Answer--hormone produced in fat cells -stimulates the satiety pathway and inhibits the hunger pathway ghrelin - Answer-stimulates the NPY pathway (hunger) amphetamine-like drugs - Answer--short term management of obesity (appetite suppressant) ADR: weight rebound orlistat - Answer-irreversible inhibitor of GI lipase (decreases fat absorption) ADR: oily spotting, flatulence, fecal urgency, oily stool, decreased absorption of fat soluble vitamins phentermine/topiramate - Answer-appetite suppressant *no rebound ADR: fetal toxicity, SUICIDAL IDEATION, glaucoma, insomnia, increased HR and bp, DSYGEUSIA (metal taste disturbance) lorcaserin - Answer-selective 5-HT2C receptor agonist *rebound effect and weight loss plateau ADR: HA, dizziness, nausea bupropion/naltrexone - Answer-antidepressant and opiate receptor antagonist ADR: insomnia, SUICIDAL IDEATION, increased HR and bp, nausea, HA, dizziness, dry mouth *contraindicated in pts with opioid dependency liraglutide - Answer-GLP-1 mimetic ADR: diarrhea, pancreatitis, N/V cellulose-citric acid polymer - Answer-hydrogel that takes up water and expands with the stomach *medical device ADR: diarrhea, abdominal pain/distension, constipation