) 4/ 4 pts
Question 1 ’
Match these tumor suppressor genes to their normal cellular
functions;
ARF MDM2antagonist Vv
BRCA2 DNA repair in homologe
SMAD4 TGF-beta signaling v
E-cadherin Cell-cell adhesion v
, = 4/ 4 pts
Question 2 5
Match these familial cancer syndromes to the TSGs they are
associated with;
Li-Fraumeni syndrome TP53 v
Familial Breast cancer BRCA1 v
Familial Juvenile SMAD4 v
Polyposis
Melanoma ARE 7
Question 1 ’
Match these tumor suppressor genes to their normal cellular
functions;
ARF MDM2antagonist Vv
BRCA2 DNA repair in homologe
SMAD4 TGF-beta signaling v
E-cadherin Cell-cell adhesion v
, = 4/ 4 pts
Question 2 5
Match these familial cancer syndromes to the TSGs they are
associated with;
Li-Fraumeni syndrome TP53 v
Familial Breast cancer BRCA1 v
Familial Juvenile SMAD4 v
Polyposis
Melanoma ARE 7
