NR293 Final Exam (New-2023, Version-2)/ NR
293 Final Exam / NR293 Pharmacology Final
Exam / NR293 Pharm Final: Chamberlain College
of Nursing (100% Verified Questions & Answers)
1). Adrenergic drugs
Ans: -centrally and peripherally acting adrenergic neuron blockers
-centrally acting alpha2 receptor agonists
-peripherally acting alpha1 receptor blockers
-peripherally acting beta receptor blockers
-peripherally acting dual alpha1 and beta receptor blockers
2). Centrally acting alpha2 receptor agonists
Ans: -stimulate alpha2-adrenergic receptors in the brain
-decrease sympathetic outflow from CNS
-decrease norepinephrine production
-stimulate renin activity in the kidneys
-decrease blood pressure
Ex: clonidine (catapres), methyldopa (aldomet)
3). Clonidine
Ans: useful in management of withdrawal symptoms in opioid-dependent person
4). Peripherally acting alpha1 receptor agonists
Ans: "azosin"
-block alpha1-adrenergic receptors
-management of severe HF when used with glycosides and diuretics
-some used to relieve symptoms of BPH (flomax)
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, 5). "azosin" adverse effects
Ans: hypotension (first dose)
syncope
diziness
6). Beta blockers "olol"
Ans: Reduce BP by reducing heart rate
-cause reduced secretion of renin
-long term use causes peripheral vascular resistance
-improve survival after MI
Ex: nebivolol, propanolol, atenolol
7). Dual action alpha1 and beta receptor blockers
Ans: reduce HR (beta1)
cause vasodilation (alpha 1)
result in decreased BP
-Carvediolol, labetalol
8). Adrenergic adverse effects
Ans: high incidence of orthostatic hypotension
bradycardia w/reflex tachycardia
sexual dysfunction
dry mouth
drowsiness, sedation
constipation
depression
edema
9). Less common adrenergic adverse effects
Ans: headache
sleep disturbances
nausea
rash
cardiac disturbances (palpitations)
10). Ace inhibitors "pril"
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, Ans: inhibit angiotensin-converting enzyme preventing angiotensin 1 from being
converted to angiotensin 2
-decreased systemic vascular resistance (afterload)
-vasodilation
-decreased blood pressure
11). Angiotensin 2
Ans: potent vasoconstrictor
causes aldosterone secretion from the adrenal glands
12). Indications for ace inhibitors
Ans: -first line drugs for HF and HTN
-slow progression of left ventricular hypertrophy after MI
-renal protective effects in patients with diabetes
13). Captopril and lisinopril
Ans: ACE inhibitors
-can be used if patient has liver dysfunction
-not prodrugs
14). Prodrugs
Ans: inactive in administered form and must be metabolized in the liver to an active
form to be effective
15). "pril" adverse effects
Ans: hyperkalemia
angioedema
dry, nonproductive cough (reverses when therapy is stopped)
16). Angiotensin ii receptor blockers "sartan"
Ans: -block receptors that receive angiotensin II
-block vasoconstriction and release of aldosterone
-well tolerated, do not cause cough
Ex: losartan, valsartan
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, 17). Indications for arb
Ans: HTN
adjunctive drugs for the treatment of HF
18). "sartan" arb adverse effects
Ans: URI
Headache
occasional dizziness
inability to sleep
diarrhea
dyspnea
hearburn
nasal congestion
back pain
fatigue
19). Calcium channel blockers
Ans: cause smooth muscle relaxation by blocking the binding of calcium to its
receptors, preventing smooth muscle contraction
20). Indications for calcium channel blockers
Ans: HTN
Angina
dysrhythmias
migraine headaches
raynaud's disease
21). Diuretics
Ans: decrease plasma and extracellular fluid volumes
-decreased workload of the heart and decreased BP
22). Thiazide diuretics
Ans: first-line antihypertensives
23). Vasodilators
PaperStoc.com Page 4 of 37
293 Final Exam / NR293 Pharmacology Final
Exam / NR293 Pharm Final: Chamberlain College
of Nursing (100% Verified Questions & Answers)
1). Adrenergic drugs
Ans: -centrally and peripherally acting adrenergic neuron blockers
-centrally acting alpha2 receptor agonists
-peripherally acting alpha1 receptor blockers
-peripherally acting beta receptor blockers
-peripherally acting dual alpha1 and beta receptor blockers
2). Centrally acting alpha2 receptor agonists
Ans: -stimulate alpha2-adrenergic receptors in the brain
-decrease sympathetic outflow from CNS
-decrease norepinephrine production
-stimulate renin activity in the kidneys
-decrease blood pressure
Ex: clonidine (catapres), methyldopa (aldomet)
3). Clonidine
Ans: useful in management of withdrawal symptoms in opioid-dependent person
4). Peripherally acting alpha1 receptor agonists
Ans: "azosin"
-block alpha1-adrenergic receptors
-management of severe HF when used with glycosides and diuretics
-some used to relieve symptoms of BPH (flomax)
PaperStoc.com Page 1 of 37
, 5). "azosin" adverse effects
Ans: hypotension (first dose)
syncope
diziness
6). Beta blockers "olol"
Ans: Reduce BP by reducing heart rate
-cause reduced secretion of renin
-long term use causes peripheral vascular resistance
-improve survival after MI
Ex: nebivolol, propanolol, atenolol
7). Dual action alpha1 and beta receptor blockers
Ans: reduce HR (beta1)
cause vasodilation (alpha 1)
result in decreased BP
-Carvediolol, labetalol
8). Adrenergic adverse effects
Ans: high incidence of orthostatic hypotension
bradycardia w/reflex tachycardia
sexual dysfunction
dry mouth
drowsiness, sedation
constipation
depression
edema
9). Less common adrenergic adverse effects
Ans: headache
sleep disturbances
nausea
rash
cardiac disturbances (palpitations)
10). Ace inhibitors "pril"
PaperStoc.com Page 2 of 37
, Ans: inhibit angiotensin-converting enzyme preventing angiotensin 1 from being
converted to angiotensin 2
-decreased systemic vascular resistance (afterload)
-vasodilation
-decreased blood pressure
11). Angiotensin 2
Ans: potent vasoconstrictor
causes aldosterone secretion from the adrenal glands
12). Indications for ace inhibitors
Ans: -first line drugs for HF and HTN
-slow progression of left ventricular hypertrophy after MI
-renal protective effects in patients with diabetes
13). Captopril and lisinopril
Ans: ACE inhibitors
-can be used if patient has liver dysfunction
-not prodrugs
14). Prodrugs
Ans: inactive in administered form and must be metabolized in the liver to an active
form to be effective
15). "pril" adverse effects
Ans: hyperkalemia
angioedema
dry, nonproductive cough (reverses when therapy is stopped)
16). Angiotensin ii receptor blockers "sartan"
Ans: -block receptors that receive angiotensin II
-block vasoconstriction and release of aldosterone
-well tolerated, do not cause cough
Ex: losartan, valsartan
PaperStoc.com Page 3 of 37
, 17). Indications for arb
Ans: HTN
adjunctive drugs for the treatment of HF
18). "sartan" arb adverse effects
Ans: URI
Headache
occasional dizziness
inability to sleep
diarrhea
dyspnea
hearburn
nasal congestion
back pain
fatigue
19). Calcium channel blockers
Ans: cause smooth muscle relaxation by blocking the binding of calcium to its
receptors, preventing smooth muscle contraction
20). Indications for calcium channel blockers
Ans: HTN
Angina
dysrhythmias
migraine headaches
raynaud's disease
21). Diuretics
Ans: decrease plasma and extracellular fluid volumes
-decreased workload of the heart and decreased BP
22). Thiazide diuretics
Ans: first-line antihypertensives
23). Vasodilators
PaperStoc.com Page 4 of 37
