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Chapter 10 - Ethical Issues in First Time Organ Surgeries Questions with well detailed answers

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Chapter 10 - Ethical Issues in First Time Organ Surgeries Louis Washkansky aka "Washy" - Answer--Suffered from end-stage cardiac disease, diabetes, coronary artery disease, congestive heart failure -Developed fulminant pulmonary edema (sign of imminent death) while waiting for a heart donor Denise Darvall and Edward Darvall - Answer--Denise was involved in a car accident crushing her head - Barnard told Edward that he had a patient in the hospital that could be saved if they used his daughters heart -Edward said "If you can't say my daughter, try and save this man" -Denise was declared dead after her heart stopped and surgeons opened her up preparing it for Barnard's excision Washy's surgery - Answer--operation took place on December 3, 1967 -Washy was given drugs to produce paralysis and prevent spontaneous breathing and placed on a heart lung machine -Washy's femoral artery was narrowed by buildup of cholesterol and the machine couldn't force blood into his heart -the pressure of the tube climbed to 290 mmHg - reattached the tube to his aorta - pressure dropped -Sewed Denis Darvall's hearth with its attached wall to Washy's chest -heart started after some false attempts -One hour later Washy regained consciousness and tried to talk What did Barnard give Washy to compact immunological rejection of the heart? - Answer-Gamma ray radiation and administered immunosuppressive drugs prednisone (steroids) and azathioprine What two procedures did Barnard force onto Washy? - Answer-Insertion of a NG tube and the reopening of his tracheotomy hole to insert a respirator What signs was Washy presenting that signified rejection? - Answer--mottled patches on his legs that indicated circulatory failure -ominous patches on his lungs - turned out to be bilateral pneumonia (klebsiella and pseudomonas) -severe pain in his chest

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Chapter 10 - Ethical Issues in First Time
Organ Surgeries
Louis Washkansky aka "Washy" - Answer--Suffered from end-stage cardiac disease, diabetes,
coronary artery disease, congestive heart failure
-Developed fulminant pulmonary edema (sign of imminent death) while waiting for a heart donor

Denise Darvall and Edward Darvall - Answer--Denise was involved in a car accident crushing
her head
- Barnard told Edward that he had a patient in the hospital that could be saved if they used his
daughters heart
-Edward said "If you can't say my daughter, try and save this man"
-Denise was declared dead after her heart stopped and surgeons opened her up preparing it for
Barnard's excision

Washy's surgery - Answer--operation took place on December 3, 1967
-Washy was given drugs to produce paralysis and prevent spontaneous breathing and placed
on a heart lung machine
-Washy's femoral artery was narrowed by buildup of cholesterol and the machine couldn't force
blood into his heart
-the pressure of the tube climbed to 290 mmHg -> reattached the tube to his aorta -> pressure
dropped
-Sewed Denis Darvall's hearth with its attached wall to Washy's chest
-heart started after some false attempts
-One hour later Washy regained consciousness and tried to talk

What did Barnard give Washy to compact immunological rejection of the heart? - Answer-
Gamma ray radiation and administered immunosuppressive drugs prednisone (steroids) and
azathioprine

What two procedures did Barnard force onto Washy? - Answer-Insertion of a NG tube and the
reopening of his tracheotomy hole to insert a respirator

What signs was Washy presenting that signified rejection? - Answer--mottled patches on his
legs that indicated circulatory failure
-ominous patches on his lungs -> turned out to be bilateral pneumonia (klebsiella and
pseudomonas)
-severe pain in his chest

On what day did Washy die and why? - Answer-December 21, 18 days after his heart transplant
because infection overran his lungs and he suffocated

After performing this the heart transplant, Christian Bernard became extremely famous and
notorious for bedding famous women. When he developed arthritis and could no longer perform
he took $4 million for saying that a facial cream named "glygel" reverses aging. What happened
when he said this? - Answer-He was expelled from the American College of Surgeons and a
cardiology society

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