Chamberlain.
Hematologic system consists of
blood and the sites where blood is produced
Blood is composed of
plasma and various types of cells:
- RBC
- WBC
- Platelets
Plasma is
fluid portion consisting of various proteins, such as:
- albumin
- globulin
- fibrinogen
- electrolytes
- waste products
- nutrients
Bone Marrow contains
stem cells committed to produce specific types of blood cells
Erythrocytes
Red Blood Cells (RBCs): delivers oxygen to tissues/body cells
Erythropoiesis
formation of red blood cells (myeloid stem cell)
Erythropoietin
hormone produced by primarily kidney
Leukocytes
white blood cells (WBCs):
protect the body from invasion by bacteria
Granulocytes
eosinophils
basophils
neutrophils
, Monocytes
transform into macrophages
Lymphocytes
immune system: produce antibodies
Platelets (thrombocytes)
essential role in the control of bleeding
Hemostasis
process of preventing blood loss from intact vessels and stopping bleeding from a severed vessel
Spleen
Location: upper left quadrant of abdomen
- Removes old RBC's
- Stores platelets and WBC's
- Helps fight certain bacteria that can cause pneumonia and meningitis (vaccination important)
Liver
Filter, procoagulants essential to hemostasis
Lymph system
- lymph fluid
- lymphatic capillaries
- ducts and lymph nodes
- primary function of nodes is filtration of pathogens and foreign particles
Red Blood Cell (RBCs)
Transport oxygen to the body's cells
Expected Range:
- Female: 4.2 - 5.4 million/uL
- Male: 4.7 - 6.1 million/uL
White Blood Cell (WBCs)
help to fight infections and diseases
Expected Range:
- 5,000 - 10,000
Elevated: Leukocytosis (infection, inflammation)