Biochem 1005 final exam study guide- Week 9 Questions & Answers 100% Correct!

Control fatty acid synthesis or oxidation: when insulin is HIGH- - ANSWERSfatty acid synthesis Control fatty acid synthesis or oxidation: When glucagon is HIGH- - ANSWERSLipolysis, fatty acid B-oxidation and ketogenesis Lipolysis - ANSWERSprocess of releasing free fatty acids from triacylglycerols stored int eh adipose in the fasted state. Lipolysis: Hormone sensitive lipase - ANSWERS-activated by glucagon and epinephrine -Triacylglycerols are hydrolyzed into: Fatty acids and glycerol -Insulin inhibits this process Lipolysis: Free fatty acids (long chain fatty acids)- - ANSWERStravel bound to albumin to peripheral tissues to be used as a source of energy Lipolysis: Glycerol travels to the liver- - ANSWERSused as a substrate for gluconeogenesis Lipolysis: Acy-CoA syntetase: - ANSWERS-can re-convert free fatty acids to acyl-COA. These can be used for re-esterification in the adipose ( continuous cycle of lipolysis and reesterification. B-oxidation (mitochondria pathway) - ANSWERSprocess of generating acetly-CoA, NADH and FADH2 from the oxidation of free fatty acids taken up by the peripheral tissues (primary live and skeletal muscle) B-oxidation (mitochondria pathway) - ANSWERSLong chain fatty acids cannot cross the mitochondrial memebrane and a transport system is in place for this to occur. B-oxidation (mitochondria pathway) Acyl-CoA synthetase - ANSWERSadds an acyl-CoA to free fatty acids B-oxidation (mitochondria pathway) Fatty acyl-CoAs are transferred to carnitine using: - ANSWERS-Carnitine palmitoyl transferase 1- generates a fatty acyl-carnitine *