Solutions.
drug
any chemical that can affect living processes
pharmacology
the study of drugs and their interactions with living systems
-physical and chemical properties of drugs
-biochemical and physiologic effects of drugs
-includes knowledge, history, sources, and uses of drugs
clinical pharmacology
the study of drugs in humans
includes: patients AND healthy volunteers (during new development)
therapeutics or pharmacotherapeutics
the use of drugs to diagnose, prevent, or treat disease or to prevent pregnancy
the medical use of drugs
effectiveness, safety, selectivity
There is no such thing as a perfect drug. However, the three MOST IMPORTANT drug
CHARACTERISTICS/properties of an IDEAL DRUG are:
effective
a ___ drug is one that elicits the responses for which it is given. *The most important
property a drug can have*
safe
a ___ drug is one that cannot produce harmful effects--even if administered at very high
doses for a very long time.
anticancer
certain ___ drugs (cyclophosphamide, methotrexate) at usual therapeutic doses, always
increase the risk of serious infection
opioid
___ analgesics (morphine, meperidine) at high therapeutic doses, can case potentially
fatal respiratory depression
aspirin
___ and related drugs, when taken long term in high therapeutic doses, can cause life
threatening gastric ulceration, perforation, and bleeding
remedy, poison
Clearly, drugs have both benefits and risks. Greeks used the word pharmakon which
means ___ and ___
selective
a ___drug is one that elicits ONLY the response for which it is given. THERE IS NO
SUCH THING as a wholly .... drug because all drugs can cause side effects.
EX: drowsiness caused by antihistamines; peripheral edema caused by calcium
channel blockers (CCBs); & the sexual dysfunction commonly caused by certain
antidepressants
additional properties of an ideal drug