NU 578 Exam Questions With Answers, Latest Updated 2024/2025 (Graded A+)

abused prescription drug, second-most - ANSWER codeine Act also known as the Controlled Substance Act (1970) - ANSWER Comprehensive Drug Abuse Prevention and Control Act actiq - ANSWER transmuscosal fentanyl only approved for breakthrough cancer pain in opioid tolerant patients addictive drugs all activate the brain's _________ - ANSWER dopamine reward circuit after detox, an opioid addict can be rx'd ___________ to discourage renewed opioid abuse - ANSWER naltrexone AIDS patients use Dronabinol (marinol) - ANSWER for appetite stim alvimopan - ANSWER used for tx of opioid-induced ileus amphetamines are schedule - ANSWER II amphetamines work primarily by promoting neuronal release of _________ & ___________, and partly by blocking their reuptake - ANSWER norepinephrine; dopamine amphetamines, most common adverse effects - ANSWER insomnia; weight loss analgesics, most effective available - ANSWER opioids avinza - ANSWER extended release morphine barbiturate OD antidote? - ANSWER none, just supportive treatment barbiturate OD produces same classic triad of symptoms (resp. depression, coma, pinpoint pupils) as seen with - ANSWER opioid OD barbiturate tolerant individuals are cross-tolerant to other CNS depressants (alcohol, benzos, general anesthetics) but not with ________ - ANSWER opioids behavior pattern characterized by continued use of a psychoactive substance despite physical, psychologic, or social harm - ANSWER addiction NU 578 Controlled Substances Quiz | Exam Questions With Answers Graded A+ benzodiazepine principal indications are - ANSWER anxiety, insomnia, seizure disorders benzodiazepines adverse effects - ANSWER daytime sedation; anterograde amnesia benzodiazepines are classified as Schedule - ANSWER IV benzodiazepines are primarily for which two anxiety d/o's - ANSWER panic disorder, GAD benzodiazepines produce their actions by enhancing the effects of _____, the principal inhibitory neurotransmitter in the CNS - ANSWER GABA benzodiazepines-like controlled substace approved for long-term use in insomnia - ANSWER eszopiclone (Lunesta) black box warnings - ANSWER a component of REMS bridging agents commonly abused - ANSWER methadone, tramadol, buprenorphine (suboxone) buprenorphine formulations used in management of opioid addiction - ANSWER subutex or suboxone SL butorphanol (stadol) and nalbuphne (nubain) are contraind. In MI as they - ANSWER increase cardiac work butrans transdermal sites must be rotated. No site may be reused within ___ days - ANSWER 21 cancer pain - ANSWER frequently undertreated, able to be mitigated in 90% of cases with proper dosing/drug therapy (consider adjuvants) chronic opioid therapy candidates can be identified with - ANSWER ORT (opioid risk tool); SOAPP (screener and opioid assessment for patients with pain); DIRE (diagnois, intractability, risk, and efficacy score) chronic opioid therapy fails - ANSWER 50-70% of the time code of fed regulations, title 21, section 1306 governs - ANSWER issuance & filling of prescriptions codeine by itself is a schedule ___ CS. In cough meds, it's often schedule ___ - ANSWER II, V complement effects of opioids (in combo with, not in substitution of) - ANSWER adjuvant analgesics Comprehensive Drug Abuse Prevention and Control Act (1970) - ANSWER establishes regulations for controlled substances for manufacturers, prescribers, pharmacists, and distributors Comprehensive Drug Abuse Prevention and Control Act (1970) aka - ANSWER Controlled Substance Act controlled substance definition - ANSWER any drug whose use is controlled by fed gov. controlled substance prescriptions require - ANSWER actual number & numerical value cross-tolerance does not exist between opioid agonists and - ANSWER general CNS depressants cross-tolerance exists among - ANSWER various opioid agonists DEA only regs dispensing of controlled subs, T or F - ANSWER FALSE depression treatment for individuals that did not respond to other tx may include stimulants, T or F - ANSWER TRUE Dronabinol (marinol - ANSWER appetite stimulant drug classes most often used for tx of anxiety disorders - ANSWER benzos; SSRIs drug only available through Opioid Treatment Programs - ANSWER methadone drug that has the ability to support physical dependence on another drug is said to have - ANSWER cross-dependence drug use that is inconsistent with medical or social norms - ANSWER abuse drugs that activate mu and kappa receptors, producing analgesia, sedation, euphoria, resp. depression, physical dependence, constipation, and cough supression - ANSWER pure opioid agonists drugs that block the mu & kappa receptors to cause reversal of sedation/resp. depression caused by opioid overdose - ANSWER opioid antagonists enforcing agency for the Comprehensive Drug Prevention & Control Act 1970 - ANSWER DEA equianalgesic table: switching opioids (other than fentanyl or methadone), decrease the dose rec. in the table by __________ % to account for polymorphisms or enhanced sensitivity to new opioids - ANSWER 25-50 establishes regulations for controlled substances for manufacturers, prescribers, pharmacists, and distributors - ANSWER Comprehensive Drug Abuse Prevention and Control Act Evzio, aka ____________, was fast-tracked through FDA approval to help prevent OD on rx or illicit opioids - ANSWER naloxone auto-injector pen extended release morphine is called - ANSWER avinza Fentanyl - ANSWER 100 times more potent than morphine fentanyl patch use education: warn pts to avoid exposing patch to _______, because doing so can accelerate drug release - ANSWER direct heat fentanyl products ARE/ARE NOT interchangeable on an mg-by-mg basis - ANSWER ARE NOT Flumazenil - ANSWER can be used to treat benzo OD Flumazenil - ANSWER a benzo receptor antagonist half-life of naloxone is ___________ than half-lives of opioids - ANSWER SHORTER hydrocodone sustained-release formulation that has no abuse-deterrent properties and therefore its approval is currently being called to be revoked - ANSWER zohydro hyperalgesia - ANSWER the emergence of a new pain syndrome refractory to tx & is atypical or unrelated to original pain