AMNH Genetics, Genomics, Genethics for Nursing
Questions and Answers for AMNH Quiz
Question 1
A patient is 34 years old and concerned about possibly being a carrier for HNPCC because his
father died of colon cancer at 39, his father’s sister died of colon cancer at age 41, and his
brother (aged 37) now has colon cancer. The brother’s testing is negative for all the known
mutations associated with inherited forms of colon cancer. How should this patient be
counseled about his risk for colon cancer? Select one:
a. Explain that testing for him would be of no benefit because of the current test
limitations but that his family history does place him a high risk.
b. Explain that his risk is not related to his brother’s diagnosis because he did not inherit
any genes from him but that since his father is a first-degree relative, testing should be
considered.
c. Explain that because the brother with cancer is negative for these gene mutations, this
cancer is most likely sporadic and his risk is the same as general population risk.
d. Explain that he could benefit from testing even though his brother is negative for these
mutations because reduced penetrance might account for his negative status.
Question 2
Which type of genetic testing is the most sensitive method for detecting any mutation in a
specific gene?
Select one:
a. Direct DNA sequencing
b. Immunohistochemistry
c. Fluorescence in situ hybridization
d. Banded chromosomal analysis
Question 3
Which tissue is most likely to provide an adequate DNA sample for genetic testing?
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https://www.coursehero.com/file/43178699/AMNH-Genetics-Quizdocx/
, Select one:
a. A mummy’s tooth
b. Nasal epithelial cells
c. Mature red blood cells
d. Distal ends of hair shafts
Question 4
Which lethal cardiac arrhythmia can occur as a complication of long QT syndrome?
Select one:
a. Atrial node reentry tachycardia
b. Prolonged atrial fibrillation
c. Torsade de
Pointes
d. Mitral valve prolapse
Question 5
What would be the expected response to a skin injury if the involved tissue had lost the normal
cell characteristic of contact inhibition?
Select one:
a. Excessive growth of replacement tissue
b. Replacement with scar tissue rather than skin
c. Failure of the wound to close
d. Displacement of skin cells into other body tissues
Question 6
What would be the patient’s response to a normal drug dose that because of a genetic
variation in an enzyme that prepares the drug for elimination results in a blood drug level that
is below the minimum effective concentration (MEC)?
Select one:
a. The drug’s duration of action is longer than expected.
b. The risk for toxic side effects is increased.
c. Drug entry exceeds drug elimination
d. The intended response fails to be produced.
Question 7
Which statement best describes the role of tumor suppressor genes in cancer development?
Select one:
This study source was downloaded by 100000849435247 from CourseHero.com on 04-22-2024 09:50:44 GMT -05:00
https://www.coursehero.com/file/43178699/AMNH-Genetics-Quizdocx/
Questions and Answers for AMNH Quiz
Question 1
A patient is 34 years old and concerned about possibly being a carrier for HNPCC because his
father died of colon cancer at 39, his father’s sister died of colon cancer at age 41, and his
brother (aged 37) now has colon cancer. The brother’s testing is negative for all the known
mutations associated with inherited forms of colon cancer. How should this patient be
counseled about his risk for colon cancer? Select one:
a. Explain that testing for him would be of no benefit because of the current test
limitations but that his family history does place him a high risk.
b. Explain that his risk is not related to his brother’s diagnosis because he did not inherit
any genes from him but that since his father is a first-degree relative, testing should be
considered.
c. Explain that because the brother with cancer is negative for these gene mutations, this
cancer is most likely sporadic and his risk is the same as general population risk.
d. Explain that he could benefit from testing even though his brother is negative for these
mutations because reduced penetrance might account for his negative status.
Question 2
Which type of genetic testing is the most sensitive method for detecting any mutation in a
specific gene?
Select one:
a. Direct DNA sequencing
b. Immunohistochemistry
c. Fluorescence in situ hybridization
d. Banded chromosomal analysis
Question 3
Which tissue is most likely to provide an adequate DNA sample for genetic testing?
This study source was downloaded by 100000849435247 from CourseHero.com on 04-22-2024 09:50:44 GMT -05:00
https://www.coursehero.com/file/43178699/AMNH-Genetics-Quizdocx/
, Select one:
a. A mummy’s tooth
b. Nasal epithelial cells
c. Mature red blood cells
d. Distal ends of hair shafts
Question 4
Which lethal cardiac arrhythmia can occur as a complication of long QT syndrome?
Select one:
a. Atrial node reentry tachycardia
b. Prolonged atrial fibrillation
c. Torsade de
Pointes
d. Mitral valve prolapse
Question 5
What would be the expected response to a skin injury if the involved tissue had lost the normal
cell characteristic of contact inhibition?
Select one:
a. Excessive growth of replacement tissue
b. Replacement with scar tissue rather than skin
c. Failure of the wound to close
d. Displacement of skin cells into other body tissues
Question 6
What would be the patient’s response to a normal drug dose that because of a genetic
variation in an enzyme that prepares the drug for elimination results in a blood drug level that
is below the minimum effective concentration (MEC)?
Select one:
a. The drug’s duration of action is longer than expected.
b. The risk for toxic side effects is increased.
c. Drug entry exceeds drug elimination
d. The intended response fails to be produced.
Question 7
Which statement best describes the role of tumor suppressor genes in cancer development?
Select one:
This study source was downloaded by 100000849435247 from CourseHero.com on 04-22-2024 09:50:44 GMT -05:00
https://www.coursehero.com/file/43178699/AMNH-Genetics-Quizdocx/
