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NUR-BIO 106 GENETICS NOTES TO IMPROVE YOUR SKILLS 100% CERTIFIED

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- Any 2 people in a room only differ in approximately 0.5% of their DNA - “Golden state killer” was able to be linked to previous crimes through his daughters DNA - Genetics help playing a role in healthcare, predicting, understanding, and treating disease o Knowing your genetics gives you options - Genetics: the study of inherited traits and variation - Traits could include hair color, eye color, height o Variation is differences in the traits between organisms ex: redhead vs brown hair - Transmission Genetics: study of the pattern of inheritance of specific traits o “Pedigree Analysis” to study human inheritance - Cytogenetics: Study chromosome number of structures o ‘karyotypes” are arranged of chromosome photos that allow one to observe them - Molecular Genetics: Discover, isolate, and manipulate specific genes - “Recombinant DNA technology” allows for physical manipulation of DNA - POPULATION GENETICS: study variations within large populations - 20,500 genes in our genomes - Don’t eat taco bell chicken its horse meat 1/20 - Pancreas produces insulin - Gene expression shows whether gene is active or not o Only 1.5% of the genome codes are turned on and producing protein (called the exome)  The other 98.5% tells the cell when/where to turn a gene on/off - Chromosomes reside within the nucleus of a cell - Everything outside of the nucleus is called cytoplasm, which contains organelles o Protein resides in cytoplasm - Transcription: the synthesis of protein of mRNA from DNA - Translation: the synthesis of protein from mRNA - Once mRNA leaves nucleus it is translated into a protein o Proteins made of amino acids  20 amino acids to make protein - Connecting 2 amino acids while making a protein makes a peptide bond between amino acids - The order of amino acids in a protein determines the folded shape of a protein - Denatured = fallen apart 1/25/2022 - DNA contains 2 strands bound together o The molecule is twisted o One strand is oriented in one direction, the other strand is oriented in the opposite direction 1/27/22 - Difference between DNA and RNA o DNA is double stranded, and RNA is generally single stranded o DNA has deoxyribose as the sugar and RNA has ribose as the sugar o Bases used in DNA consist of  Thymine (T)  Cytosine (C)  Adenine (A)  Guanine (G) o Bases in RNA consist of  Uracil (U)  Cytosine ©  Adenine (A)  Guanine (G) - The enzyme that synthesizes RNA is RNA polymerase o RNA polymerase “rides” along the DNA template while it synthesizes RNA o The promoter is an upstream sequence of DNA that tells the polymerase where to start

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NUR-BIO 106 GENETICS NOTES
TO IMPROVE YOUR SKILLS 100%
CERTIFIED
Bio 106 notes:


- Any 2 people in a room only differ in approximately 0.5% of their DNA

- “Golden state killer” was able to be linked to previous crimes through his daughters
DNA

- Genetics help playing a role in healthcare, predicting, understanding, and treating
disease

o Knowing your genetics gives you options

- Genetics: the study of inherited traits and variation

- Traits could include hair color, eye color, height

o Variation is differences in the traits between organisms ex: redhead vs brown

hair

- Transmission Genetics: study of the pattern of inheritance of specific traits

o “Pedigree Analysis” to study human inheritance

- Cytogenetics: Study chromosome number of structures

o ‘karyotypes” are arranged of chromosome photos that allow one to observe

them

- Molecular Genetics: Discover, isolate, and manipulate specific genes

- “Recombinant DNA technology” allows for physical manipulation of DNA

- POPULATION GENETICS: study variations within large populations

- 20,500 genes in our genomes

,NUR-BIO 106 GENETICS NOTES
TO IMPROVE YOUR SKILLS 100%
CERTIFIED
- Don’t eat taco bell chicken its horse meat




1/20

- Pancreas produces insulin

- Gene expression shows whether gene is active or not

o Only 1.5% of the genome codes are turned on and producing protein (called the

exome)

 The other 98.5% tells the cell when/where to turn a gene on/off

- Chromosomes reside within the nucleus of a cell

- Everything outside of the nucleus is called cytoplasm, which contains organelles

o Protein resides in cytoplasm

- Transcription: the synthesis of protein of mRNA from DNA

- Translation: the synthesis of protein from mRNA

- Once mRNA leaves nucleus it is translated into a protein

o Proteins made of amino acids

 20 amino acids to make protein

- Connecting 2 amino acids while making a protein makes a peptide bond between amino

acids

- The order of amino acids in a protein determines the folded shape of a protein

, NUR-BIO 106 GENETICS NOTES
TO IMPROVE YOUR SKILLS 100%
CERTIFIED
- Denatured = fallen apart

1/25/2022

- DNA contains 2 strands bound together

o The molecule is twisted

o One strand is oriented in one direction, the other strand is oriented in the

opposite direction

1/27/22

- Difference between DNA and RNA

o DNA is double stranded, and RNA is generally single stranded

o DNA has deoxyribose as the sugar and RNA has ribose as the sugar

o Bases used in DNA consist of

 Thymine (T)

 Cytosine (C)

 Adenine (A)

 Guanine (G)

o Bases in RNA consist of

 Uracil (U)

 Cytosine ©

 Adenine (A)

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