ALU 301 Exam study Guide |Questions with Complete
Solutions
Cells that can recognize altered surface molecules on mutated host cells as "foreign" and move to
destroy the cell that carries them are:
1. Complements
2. Receptors
3. Natural Killers
4. Mediators
Natural Killers
All of the following are common examples of autoimmune disease EXCEPT:
1. Hashimoto's thyroiditis
2. Rheumatoid arthritis
3. Graves' Thyroid Disease
4. Poliomyelitis
Poliomyelitis
Which of the following statements regarding serum immunoglobulin levels is/are correct?
A. Monoclonal gammopathy is a risk for transformation into multiple myeloma.
B. Polyclonal gammopathy is frequently associated with chronic infections.
C. Low serum globulin can indicate a primary immune deficiency.
1. A only
2. B only
3. A and C only
4. All of the above
All of the above
The type of immune cell that differentiates in the bone marrow is:
1. T-lymphocyte
2. Helper T-cells
3. Natural Killer cells
4. B-lymphocyte
B-lymphocyte
Which of the following statements regarding T-lymphocytes is/are correct:
A. One type is cytotoxic T-cells
B. They eliminate infected cells
C. They provide immunity by production of antibodies
1. A only
2. A and B only
3. B and C only
4. All of the above
A and B
,The cells of the immune system originate in the:
1. spleen
2. white blood cells
3. bone marrow
4. lymph nodes
bone marrow
A polyclonal gammopathy pattern on serum protein electrophoresis (SPEP) can indicate all of the
following EXCEPT:
1. Multiple myeloma
2. Infectious mononucleosis
3. Chronic hepatitis
4. Connective tissue disease
Multiple Myeloma
Which of the following statements regarding common variable immunodeficiency is/are correct?
A. It is a congenital disease.
B. Diarrhea is a recurring problem
C. Adults usually present with chronic sinus infections.
1. A only
2. B only
3. A and C only
4. B and C only
B and C
Functions of T-Lymphocytes include which of the following?
A. defense against cancer
B. elimination of infected cells
C. correction of errors in DNA
1. A and B only
2. A and C only
3. B and C only
4. All of the above
A and B
Which of the following is an autoimmune disease:
A. Systemic lupus
B. Idiopathic thrombocytopenia
C. Hashimoto's thyroiditis
1. A only
2. A and B
3. B and C
4. All of the above
,All of the above
All of the following about the Innate system are true EXCEPT:
1. It changes over the lifetime of an individual
2. It is very broad in ability to respond to invasive organisms
3. Response is non-specific
4. Has no immunological memory
It changes over the lifetime of an individual
Which of the following are components of the Innate system?
A. Physical barrier
B. Red Blood Cells
C. White Blood Cells
1. A only
2. A and C
3. B and C
A and C
The most abundant white blood cells in the blood count differential are:
1. Monocytes
2. Granulocytes
3. Natural Killer Cells
4. Lymphocytes
Granulocytes
This disorder results in frequent respiratory infections and chronic pulmonary disease of varying
severity is:
1. Agammaglobulinemia
2. IgA deficiency
3. CVID
4. SCID
IgA deficiency
All of the following regarding cancer immunotherapy are correct EXEPT:
1. The most difficult aspect of cancer therapy is paring the patient's normal tissue from damage while
delivering fatal treatment to cancer cells.
2. Immunotherapy with cytokines are given to enhanced the patient's own defenses.
3. Monoclonal antibodies aims the anti-cancer therapy directly at individual cancer cells without
damaging normal cells
4. Monoclonal antibodies cannot be combined with radioactive substances that are toxic to cancer
cells
Monoclonal antibodies cannot be combined with radioactive substances that are toxic to cancer cells
All of the following regarding cytokine tumor necrosis factor alpha (TNF-a) are correct EXCEPT:
, 1. It is made by deactivated macrophages and lymphocytes.
2. It enhances white blood cell cytotoxicity.
3. It promotes inflammation.
4. Are given to enhance the patient's own defenses.
It is made by deactivated macrophages and lymphocytes.
Which of the following are medications that block function and decrease the inflammatory activity
associated with Rheumatoid Arthritis?
A. Enteracept (Enbrel)
B. Adalimumab (Humira)
C. Interferon alpha
1. A only
2. A and B
3. A and C
4. All of the above
A and B
All of the following regarding Common Variable Immunodeficiency (CVID) are correct EXCEPT:
1. Must be considered in those with chronic pulmonary infections and low globulin levels.
2. It is congenital and affects stem cells.
3. It is associated with autoimmune diseases, such as rheumatoid arthritis (RA)
4. With good management, it can be mild enough to allow for near normal lifespan.
It is congenital and affects stem cells.
The disorder that causes recurrent bacterial infections of the respiratory tract, sinuses and ears (Otis
media) is:
1. IgA deficiency
2. Psoriasis
3. X-linked agammaglobulinemia
4. Systemic lupus erythematosus
X-linked agammaglobulinemia
The mainstay of treatment for acute mild to moderate ulcerative colitis is:
1. proton pump inhibitor
2. 5-aminosalicylate compounds
3. immunomodulators
4. biologic agents
5-aminosalicylate compounds
All of the following statements regarding Crohn's Disease (CD) are correct EXCEPT:
1. It involves inflammation of all layers of the bowel wall.
2. It can involve nearby lymph nodes.
3. The most common presenting symptom is a fistula.
The most common presenting symptom is a fistula.
Solutions
Cells that can recognize altered surface molecules on mutated host cells as "foreign" and move to
destroy the cell that carries them are:
1. Complements
2. Receptors
3. Natural Killers
4. Mediators
Natural Killers
All of the following are common examples of autoimmune disease EXCEPT:
1. Hashimoto's thyroiditis
2. Rheumatoid arthritis
3. Graves' Thyroid Disease
4. Poliomyelitis
Poliomyelitis
Which of the following statements regarding serum immunoglobulin levels is/are correct?
A. Monoclonal gammopathy is a risk for transformation into multiple myeloma.
B. Polyclonal gammopathy is frequently associated with chronic infections.
C. Low serum globulin can indicate a primary immune deficiency.
1. A only
2. B only
3. A and C only
4. All of the above
All of the above
The type of immune cell that differentiates in the bone marrow is:
1. T-lymphocyte
2. Helper T-cells
3. Natural Killer cells
4. B-lymphocyte
B-lymphocyte
Which of the following statements regarding T-lymphocytes is/are correct:
A. One type is cytotoxic T-cells
B. They eliminate infected cells
C. They provide immunity by production of antibodies
1. A only
2. A and B only
3. B and C only
4. All of the above
A and B
,The cells of the immune system originate in the:
1. spleen
2. white blood cells
3. bone marrow
4. lymph nodes
bone marrow
A polyclonal gammopathy pattern on serum protein electrophoresis (SPEP) can indicate all of the
following EXCEPT:
1. Multiple myeloma
2. Infectious mononucleosis
3. Chronic hepatitis
4. Connective tissue disease
Multiple Myeloma
Which of the following statements regarding common variable immunodeficiency is/are correct?
A. It is a congenital disease.
B. Diarrhea is a recurring problem
C. Adults usually present with chronic sinus infections.
1. A only
2. B only
3. A and C only
4. B and C only
B and C
Functions of T-Lymphocytes include which of the following?
A. defense against cancer
B. elimination of infected cells
C. correction of errors in DNA
1. A and B only
2. A and C only
3. B and C only
4. All of the above
A and B
Which of the following is an autoimmune disease:
A. Systemic lupus
B. Idiopathic thrombocytopenia
C. Hashimoto's thyroiditis
1. A only
2. A and B
3. B and C
4. All of the above
,All of the above
All of the following about the Innate system are true EXCEPT:
1. It changes over the lifetime of an individual
2. It is very broad in ability to respond to invasive organisms
3. Response is non-specific
4. Has no immunological memory
It changes over the lifetime of an individual
Which of the following are components of the Innate system?
A. Physical barrier
B. Red Blood Cells
C. White Blood Cells
1. A only
2. A and C
3. B and C
A and C
The most abundant white blood cells in the blood count differential are:
1. Monocytes
2. Granulocytes
3. Natural Killer Cells
4. Lymphocytes
Granulocytes
This disorder results in frequent respiratory infections and chronic pulmonary disease of varying
severity is:
1. Agammaglobulinemia
2. IgA deficiency
3. CVID
4. SCID
IgA deficiency
All of the following regarding cancer immunotherapy are correct EXEPT:
1. The most difficult aspect of cancer therapy is paring the patient's normal tissue from damage while
delivering fatal treatment to cancer cells.
2. Immunotherapy with cytokines are given to enhanced the patient's own defenses.
3. Monoclonal antibodies aims the anti-cancer therapy directly at individual cancer cells without
damaging normal cells
4. Monoclonal antibodies cannot be combined with radioactive substances that are toxic to cancer
cells
Monoclonal antibodies cannot be combined with radioactive substances that are toxic to cancer cells
All of the following regarding cytokine tumor necrosis factor alpha (TNF-a) are correct EXCEPT:
, 1. It is made by deactivated macrophages and lymphocytes.
2. It enhances white blood cell cytotoxicity.
3. It promotes inflammation.
4. Are given to enhance the patient's own defenses.
It is made by deactivated macrophages and lymphocytes.
Which of the following are medications that block function and decrease the inflammatory activity
associated with Rheumatoid Arthritis?
A. Enteracept (Enbrel)
B. Adalimumab (Humira)
C. Interferon alpha
1. A only
2. A and B
3. A and C
4. All of the above
A and B
All of the following regarding Common Variable Immunodeficiency (CVID) are correct EXCEPT:
1. Must be considered in those with chronic pulmonary infections and low globulin levels.
2. It is congenital and affects stem cells.
3. It is associated with autoimmune diseases, such as rheumatoid arthritis (RA)
4. With good management, it can be mild enough to allow for near normal lifespan.
It is congenital and affects stem cells.
The disorder that causes recurrent bacterial infections of the respiratory tract, sinuses and ears (Otis
media) is:
1. IgA deficiency
2. Psoriasis
3. X-linked agammaglobulinemia
4. Systemic lupus erythematosus
X-linked agammaglobulinemia
The mainstay of treatment for acute mild to moderate ulcerative colitis is:
1. proton pump inhibitor
2. 5-aminosalicylate compounds
3. immunomodulators
4. biologic agents
5-aminosalicylate compounds
All of the following statements regarding Crohn's Disease (CD) are correct EXCEPT:
1. It involves inflammation of all layers of the bowel wall.
2. It can involve nearby lymph nodes.
3. The most common presenting symptom is a fistula.
The most common presenting symptom is a fistula.
