Rh Systems and AHG Questions with Correct Answers

Name the scientists who first identified the Rh blood group - Correct Answer Landsteiner and Weiner Name the clinical significance of the Rh blood group - Correct Answer Primary cause of HDN and HTR; After A and B it is the most signficcant RBC antigen in transfusion practice due to high immunogenicity Describe the inheritence of the Rh genes - Correct Answer inherited as co-dominant alleles; Genes so closely liked that they are inherited as a single unit Describe the genetics of the Rh genes regarding transmission of genes - Correct Answer 2 genes residing on chromosome 1; RHD - codes for presence or absence of D polypeptide; RHCE codes for expression of CcEe List the 5 principle antigens in the Rh blood group - Correct Answer C,c,D, E, e List the genes that make up the Rh system - Correct Answer RHD gene RHCE gene List the nomenclature systems used to describe the Rh system - Correct Answer Fisher-Race Weiner Rosenfield ISBT Describe the biochemical structure of the Rh antigens - Correct Answer ... List the most common Rh haplotypes in the white and black populations - Correct Answer White - DCe Blacks - Dce List the Rh antigens using the Fisher-Race nomenclature - Correct Answer C, D, E Rh(D) negative phenotype - - Correct Answer Result of complete deletion of RHD gene Single gene compose of nucleotide sequences within gene that code for individual epitopes - Correct Answer haplotypes List the Rh antigens using the Weiner nomenclature - Correct Answer Rh0, rh', hr', rh'' and hr''