SBB Review A+ Graded

Band 3 - Correct Answer macrocomplex of proteins including: -Rh -RhAG -LW (ICAM-4) -GPA -GPB -CD47 ATP source for RBCs - Correct Answer 90% from Glycolysis (Embden-Meyerhoff pathway) 10% from pentose phosphate pathway Methemoglobin Reductase Pathway - Correct Answer necessary to maintain heme iron in ferrous (Fe2+) state Deficiency causes accumulation of methemoglobin, nonfunctional from of Hgb Leubering Rapaport Shunt - Correct Answer permits accumulation of 2,3-DPG "Tense form" of Hgb - Correct Answer DEOXYGENATED widening of beta-chain lower affinity for O2 expels 2,3-DPG "Relaxed form" of Hgb - Correct Answer OXYGENATED beta-chain pulled together higher affinity for O2 expels 2,3-DPG "Shift Right" - Correct Answer higher P50 value decreased pH (increased H+ ion), acidosis increased 2,3-DPG higher temperature high pCO2 Seen in compensated anemia "Shift Left" - Correct Answer lower P50 value increased pH (decresed H+ ion), alkalosis decreasede 2,3-DPG lower temeratures low pCO2 Seen in storage of RBC