New VERSION 2024
Quiz :What two factors impact absorption in the GI tract? - Answer :-pH-
dependent passive diffusion
-Gastric emptying time
Quiz :Absorption in premature neonates - Answer :Gastric acidity: DECREASED
Gastric emptying time: DECREASED
GI motility: DECREASED
Pancreatic enzyme activity: SIGNIFICANTLY DECREASED
GI surface area: Increased
Skin permeability: Significantly Increased
Quiz :Absorption in fullterm neonates - Answer :Gastric acidity: DECREASED
Gastric emptying time: DECREASED
GI motility: DECREASED
Pancreatic enzyme activity: DECREASED
GI surface area: Increased
Skin permeability: Increased
Quiz :Absorption in infants - Answer :Gastric acidity: DECREASED
Gastric emptying time: EQUAL
GI motility: DECREASED
Pancreatic enzyme activity: DECREASED
GI surface area: Increased
Skin permeability: EQUAL
Quiz :Absorption in child - Answer :Gastric acidity: EQUAL
Gastric emptying time: EQUAL
GI motility: EQUAL
Pancreatic enzyme activity: EQUAL
GI surface area: Increased
Skin permeability: EQUAL
Quiz :Absorption in adolescent - Answer :Gastric acidity: EQUAL
Gastric emptying time: EQUAL
GI motility: EQUAL
Pancreatic enzyme activity: EQUAL
GI surface area: EQUAL
, Skin permeability: EQUAL
Quiz :Distribution of drugs with Plasma proteins in neonates -
Answer :DECREASED and increases with age.
Quiz :Distribution of drugs with blood brain barrier in neonates -
Answer :DECREASED and increases with age
Quiz :Liver metabolism in premature neonates, full term neonates and infants
- Answer :DECREASED... increases for children and adolescents
Quiz :When does the elimination system start to mature - Answer :as children
and adolescents
Quiz :Amoxicillin used to treat - Answer :Strep throat, pneumonia, ear
infections, sinus infections
- Adjust dose in Renal Impairment
Quiz :What type of antibiotic is a beta lactam? - Answer :amoxicillin and
cephalosporins; cell wall inhibitor
Quiz :Amoxicillin dosing - Answer :General Dosing: 25 - 45 mg/kg/day in
divided doses q 12 hours
Quiz :Max dose of amoxicillin - Answer :875 mg/dose
Quiz :AOM dosing of amoxicillin - Answer :AOM: 80 - 90 mg/kg/day in divided
doses q 12 hours
Quiz :Acute Otitis Media Treatment - Answer :Amoxicillin 1st choice 80-90
mg/kg/dose
Cefdinir 2nd choice (if penicillin allergy)
Quiz :Azithromycin used for - Answer :Group A Strep
Quiz :Azithromycin dosing for Group A Strep - Answer :12 mg/kg/dose once
daily for 5 days