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NU664 FINAL EXAM QUESTIONS AND CORRECT ANSWERS 2024 LATEST VERSION

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PANDAS Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections Presentation appears like acute onset of OCD including food restriction and two or more of the following: anxiety emotional lability depression irritability opposition ADHD symptoms

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NU 664 FINAL EXAM | NU664 FINAL EXAM QUESTIONS AND
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PANDAS

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections



Presentation appears like acute onset of OCD including food restriction and two or more of the
following:

anxiety

emotional lability

depression

irritability

opposition

ADHD symptoms

Academic decline

regressive bx



MSE may reveal SIB, regressive language such as "baby talk" incongruent laughter



Treat the source of the infection, immunotherapies and anti-inflammitory treatments.

Also recommend benzo or antipsychotic agent



Symptoms may reoccur




PANS

Pediatric Acute Onset Neuropsychiatric Symptoms

Associated with bacterial or viral infections such as influenza or M. Pneumonia or lyme

Symptoms are often severe and episodic

,often accompanied by Severe separation anxiety



MSE may reveal SIB, regressive language such as "baby talk" incongruent laughter



Treat the source of the infection, immunotherapies and anti-inflammitory treatments.

Also recommend benzo or antipsychotic agent



Symptoms may reoccur




ACES

Adverse Childhood Experiences



There are 10 types of childhood trauma

5 person-physical abuse, verbal abuse, sexual abuse, physical neglect, and emotional neglect

5 family related-family substance use, domestic violence, family member in jail, family with mental
illness, and divorce of parents



Each type of trauma counts as a 1 which totals the ACE score

Questions are asked in relation to prior to 18th birthday



The ACE study was large and well known and linked childhood trauma to chronic disease states and
emotional/social problems i.e as the ACE score increases so does the risk of disease states




primary prevention

Efforts to prevent an injury or illness from ever occurring.

, secondary prevention

Efforts to limit the effects of an injury or illness that you cannot completely prevent.




tertiary prevention

actions taken to contain damage once a disease or disability has progressed beyond its early stages




Brain Plasticity Theory

Changes in brain structures in children/adults effect on ability to learn and perform tasks




monoamine theory of depression

theory that depression is at least sometimes due to absolute/relative depletion of one or both
neurotransmitters (5-HT and NE) at important receptor sites in the brain

* research has shown that depression is not this straightforward




Serotonin Syndrome

With any drug that increases 5-HT (e.g., MAO inhibitors, SNRIs, TCAs) hyperthermia, confusion,
myoclonus, cardiovascular instability, flushing, diarrhea, seizures.

-Treatment: cyproheptadine (5-HT2 receptor antagonist).




Amygdala

A limbic system structure involved in memory and emotion, particularly fear, anxiety and aggression.

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