BRD Pharmocology
QUESTIONS AND
VERIFIED ANSWERS
LATEST UPDATE 2023
Which of the following anesthetic agents has the shortest duration of action?
Sublimaze( fentanyl), Ativan (loreazepam), Diprivan (Proprofol), Sufenta (sufentanyl)? -
ANSWER Propofol (Diprivan)
Which of the following drugs increases the tolerance of the brain to global ischemia
when administered prior to ischemic episode? Dextrose 50%, Dilantin (phenytoin),
Mannitol, Pentothal (thiopenthal)? - ANSWER Pentothal (thiopenthal)
RAAS antagonist are also know as? - ANSWER Ace inhibitors
What do Ace inhibitors cause? - ANSWER block Ang l to Ang ll conversion and thus
increased UOP: They increase preload and decrease afterload
Ace inhibitors names end in? name some - ANSWER "pril", Benzepril, Captopril,
Enalapril, Quinipril
How do phosphodiesterase inhibitors work? - ANSWER blocks the breakdown of
cAMP. cAMP builds up and causes oncreased Ca++ uptake. Increase in contractility,
increases stroke volume, increases ejection fraction, increases sinus rate. Dercreases
peripheral vascular resistance. DECREASES PRELOAD and DECREASES
AFTERLOAD.
Name some Phosphodiesterase inhibitors. - ANSWER Amrinone ( Inocor) and
Milrinone (Primacor)
, Which phosphodiesterase inhibitor is more potent? - ANSWER Milrinone is 20X more
amrinone
How do cardiac glycosides work? - ANSWER inhibit the Na+/K+ ATPase pump and
increase inward current of Ca++. INCREASES CONTRACTION, INCREASE CO.
DECREASES HEART SIZE, DECREASES VENOUS RETURN, DECREASES BLOOD
VOLUME BY INCREASE DIURESIS AND INCREASED RENAL BLOOD FLOW.
Cardiac gycosides are used to treat what? - ANSWER CHF: ↓ HR and ↑ Contraction:
Slows ventricular rate during atrial flutter by increasing sensitivity of AV node. Increases
peripheral vascular resistance.
Name some cardiac glycosides. - ANSWER Digoxin (Lanoxin), Adenosine
How many classes of anti-arrhythmics are there? - ANSWER 5, Na+ channel
antagonist, Beta blockers, K_+ channel blockers, Ca++ channel blockers, cardiac
gycosides
Class l anti-arrhythmics work by what mechanism? - ANSWER Na+ channel blocker:
↓conduction velocity in atrias and His-Pukinje cells. ↑refractory period throughout heart
except nodes
Name some class l anti-arrhythmics? - ANSWER Lidocaine (Xylocaine),
Procaineamide (Pronestyl), Quinidine, Disopyramide (Norpace)
What is the normal does of Lidocaine? - ANSWER 1 mg/kg
Class II anti-arrhythmics work by? - ANSWER antagonize adrenergic receptors (beta-
blockers): ↓ HR, ↓contractility, ↓automaticity: ↑ A-V conduction time and refractory time
Name some class II antiarrhythmics - ANSWER Esmolol and Propranolol
Treats HTN
Name the selective B-blockers - ANSWER ABEAM: Atenol, bisoprolol, esmolol,
ecebutolol, metoprolol.
Treats HTN
Name some non-selective B-blockers - ANSWER Nadolol, Pindolol, Sotalol,
PROPRANOLOL, Timolol:
Treats HTN
Name some mixed alpha and beta antagonist (blockers) - ANSWER Labetolol
(trandate) and Cardvedilol (Coreg): used to treat HTN
QUESTIONS AND
VERIFIED ANSWERS
LATEST UPDATE 2023
Which of the following anesthetic agents has the shortest duration of action?
Sublimaze( fentanyl), Ativan (loreazepam), Diprivan (Proprofol), Sufenta (sufentanyl)? -
ANSWER Propofol (Diprivan)
Which of the following drugs increases the tolerance of the brain to global ischemia
when administered prior to ischemic episode? Dextrose 50%, Dilantin (phenytoin),
Mannitol, Pentothal (thiopenthal)? - ANSWER Pentothal (thiopenthal)
RAAS antagonist are also know as? - ANSWER Ace inhibitors
What do Ace inhibitors cause? - ANSWER block Ang l to Ang ll conversion and thus
increased UOP: They increase preload and decrease afterload
Ace inhibitors names end in? name some - ANSWER "pril", Benzepril, Captopril,
Enalapril, Quinipril
How do phosphodiesterase inhibitors work? - ANSWER blocks the breakdown of
cAMP. cAMP builds up and causes oncreased Ca++ uptake. Increase in contractility,
increases stroke volume, increases ejection fraction, increases sinus rate. Dercreases
peripheral vascular resistance. DECREASES PRELOAD and DECREASES
AFTERLOAD.
Name some Phosphodiesterase inhibitors. - ANSWER Amrinone ( Inocor) and
Milrinone (Primacor)
, Which phosphodiesterase inhibitor is more potent? - ANSWER Milrinone is 20X more
amrinone
How do cardiac glycosides work? - ANSWER inhibit the Na+/K+ ATPase pump and
increase inward current of Ca++. INCREASES CONTRACTION, INCREASE CO.
DECREASES HEART SIZE, DECREASES VENOUS RETURN, DECREASES BLOOD
VOLUME BY INCREASE DIURESIS AND INCREASED RENAL BLOOD FLOW.
Cardiac gycosides are used to treat what? - ANSWER CHF: ↓ HR and ↑ Contraction:
Slows ventricular rate during atrial flutter by increasing sensitivity of AV node. Increases
peripheral vascular resistance.
Name some cardiac glycosides. - ANSWER Digoxin (Lanoxin), Adenosine
How many classes of anti-arrhythmics are there? - ANSWER 5, Na+ channel
antagonist, Beta blockers, K_+ channel blockers, Ca++ channel blockers, cardiac
gycosides
Class l anti-arrhythmics work by what mechanism? - ANSWER Na+ channel blocker:
↓conduction velocity in atrias and His-Pukinje cells. ↑refractory period throughout heart
except nodes
Name some class l anti-arrhythmics? - ANSWER Lidocaine (Xylocaine),
Procaineamide (Pronestyl), Quinidine, Disopyramide (Norpace)
What is the normal does of Lidocaine? - ANSWER 1 mg/kg
Class II anti-arrhythmics work by? - ANSWER antagonize adrenergic receptors (beta-
blockers): ↓ HR, ↓contractility, ↓automaticity: ↑ A-V conduction time and refractory time
Name some class II antiarrhythmics - ANSWER Esmolol and Propranolol
Treats HTN
Name the selective B-blockers - ANSWER ABEAM: Atenol, bisoprolol, esmolol,
ecebutolol, metoprolol.
Treats HTN
Name some non-selective B-blockers - ANSWER Nadolol, Pindolol, Sotalol,
PROPRANOLOL, Timolol:
Treats HTN
Name some mixed alpha and beta antagonist (blockers) - ANSWER Labetolol
(trandate) and Cardvedilol (Coreg): used to treat HTN
