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Summary Medical - Resistance to antibiotics in children

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Medical - Resistance to antibiotics in children need to know knowledge article, beneficial to parents, doctors, nurses, schools and other medical related subjects.

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Resistance to antibiotics in children.
Antibiotic resistance in children is a growing concern globally. It occurs when bacteria that cause
infections become resistant to the antibiotics designed to kill them. This means that some antibiotics
may not work if your child needs them in the future. The misuse and overuse of antibiotics are the main
drivers in the development of drug-resistant pathogens.

The American Academy of Pediatrics emphasizes the importance of antibiotic stewardship in pediatrics,
which involves prescribing antibiotics only when necessary and, when they are considered necessary,
promoting the use of the appropriate agent(s), dose, duration, and route of therapy to optimize clinical
outcomes while minimizing the unintended consequences of antibiotic use. This is particularly important
in children, as their immune systems are not fully developed, making them less able to ward off
infections.

The World Health Organization (WHO) also highlights that antimicrobial resistance (AMR) is one of the
top global public health threats. It estimates that bacterial AMR was directly responsible for 1.27 million
global deaths in 2019 and contributed to 4.95 million deaths. AMR affects countries at all income levels,
with its drivers and consequences exacerbated by poverty and inequality.

To combat this issue, it’s crucial to prevent infections that may result in inappropriate use of
antimicrobials, ensure universal access to quality diagnosis and appropriate treatment of infections, and
promote strategic information and innovation, such as surveillance of AMR and antimicrobial
consumption/use.



What are the risks of antibiotic resistance in children?
Antibiotic resistance poses significant risks to children, who are more vulnerable to bacterial illnesses
than adults. Here are some of the risks associated with antibiotic resistance in children:

1. Increased Severity of Infections: Resistant bacteria can cause more serious infections, such as
pneumococcal infections (pneumonia, ear infections, sinus infections, and meningitis), skin
infections, and tuberculosis.
2. Higher Disease Rates: Children, especially infants under the age of one, are more likely to
contract bacterial infections like Salmonella, which can be 10 times more common in young
children than adults.
3. Treatment Challenges: With antibiotic resistance, common infections may become difficult to
treat, leading to longer-lasting infections, increased medical visits, and the use of stronger and
more expensive drugs.
4. Spread of Resistance: Children can spread resistant bacteria to other children and family
members, which can lead to outbreaks of drug-resistant infections.
5. Hospitalization: There may be an increased need for hospitalizations due to infections that are
harder to treat at home.
6. Global Health Threat: Antimicrobial resistance (AMR) is one of the top global public health
threats, affecting children worldwide and requiring strong coordination and collaboration among
different sectors to protect them.

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