Unit 4 Digestive Disease- GI tract
•Normal digestive system
1. Chronic Gastritis
2. Helicobacter pylori Gastritis
3. Autoimmune gastritis
4. Peptic ulcer
5. Gastric Adenocarcinoma
6. Inflammatory bowel disease
- Crohn’s disease
- Ulcerative colitis
7. Adenocarcinoma
1. Chronic Gastritis 慢性胃炎
• Presence of chronic inflammatory changes in the mucosa黏膜存在的慢性發炎變化
• Most common cause is infection with the bacillus Helicobacter pylori.
- Autoimmune gastritis 自體免疫性胃炎 -->. the most common cause of atrophic gastritis
萎縮性胃炎
- association with pernicious anemia 與惡性貧血有關
- Toxic, as with alcohol and cigarette smoking 有毒，如飲酒和吸煙
, - Presents less than 10% of cases of chronic gastritis 佔慢性胃炎病例的不到 10%
- most common form of chronic gastritis in patients without H. pylori infection.
也是未感染幽門螺旋桿菌的患者中最常見的慢性胃炎形式
Complication of chronic Gastritis
•Peptic ulcer Disease (PUD) 消化性潰瘍
•Mucosal atrophy and intestinal metaplasia 黏膜萎縮及腸化生
-Increase the risk of adenocarcinoma, especially in autoimmune gastritis
•Dysplasia 發育不良
•Gastric cystica 胃囊腫
Gastric acidity: gastric juice (acid ~pH 2) -->. damage stomach tissue
Peptic enzymes: enzyme will digest (kill) your own cells
Mucus: secrete mucus cell (neutralize the gastric juice), renew very fast
2. Helicobacter pylori Gastritis 幽門螺旋桿菌胃炎
•Normal digestive system
1. Chronic Gastritis
2. Helicobacter pylori Gastritis
3. Autoimmune gastritis
4. Peptic ulcer
5. Gastric Adenocarcinoma
6. Inflammatory bowel disease
- Crohn’s disease
- Ulcerative colitis
7. Adenocarcinoma
1. Chronic Gastritis 慢性胃炎
• Presence of chronic inflammatory changes in the mucosa黏膜存在的慢性發炎變化
• Most common cause is infection with the bacillus Helicobacter pylori.
- Autoimmune gastritis 自體免疫性胃炎 -->. the most common cause of atrophic gastritis
萎縮性胃炎
- association with pernicious anemia 與惡性貧血有關
- Toxic, as with alcohol and cigarette smoking 有毒，如飲酒和吸煙
, - Presents less than 10% of cases of chronic gastritis 佔慢性胃炎病例的不到 10%
- most common form of chronic gastritis in patients without H. pylori infection.
也是未感染幽門螺旋桿菌的患者中最常見的慢性胃炎形式
Complication of chronic Gastritis
•Peptic ulcer Disease (PUD) 消化性潰瘍
•Mucosal atrophy and intestinal metaplasia 黏膜萎縮及腸化生
-Increase the risk of adenocarcinoma, especially in autoimmune gastritis
•Dysplasia 發育不良
•Gastric cystica 胃囊腫
Gastric acidity: gastric juice (acid ~pH 2) -->. damage stomach tissue
Peptic enzymes: enzyme will digest (kill) your own cells
Mucus: secrete mucus cell (neutralize the gastric juice), renew very fast
2. Helicobacter pylori Gastritis 幽門螺旋桿菌胃炎
