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pathophysiology
study of functional or physiologic change that result in a disruption of normal function
physiology
normal day to day function
pathology
the directly observable lab study of cell and tissue changes associated with disease, study of
observable changes
pathologist
physician who looks for changes in cell and tissue
health
the state of an organism when it functions in homeostasis
disease
an interruption, cessation or disorder of body functions, systems or organs
homeostasis
state of equilibrium, what the body wants
negative feedback loop
output of system acts to oppose changes from the input of the system, resulting stability
positive feedback loop
output is unable to attenuate an input change resulting in an imbalance of system, often results in
disease, heart failure - the body's response makes problem worse
diagnosis
signs and symptoms together
signs
what we see
symptoms
what patient tells us
etiology
causes of the disease, how did we get the disease
, predisposing factors
risk factors for developing a disease
pathogeneisis
process of beginning the disease, goes with etiology, what caused the start of the disease
syndrome
compilation of signs and symptoms that point toward a diagnosis, AIDS - signs and lab work,
compilation of signs and symptoms together
insidious
a gradual progression with very vague of mild signs
prognosis
how bad is it? what are the chances of recovery?
morbidity
how many people have the disease, negatively affects quality of life
mortality
causes death
epidemiology
study of disease in a population
pathophysiology
identifies disease before it shows signs and symptoms, cellular changes
atrophy
loss of growth, muscle growth diminishes
hypertrophy
increase in the size of individual cells
hyperplasia
increase in the number of cells, healthy growth just more cells
metaplasia
cell changes from one cell type to another. ciliated epithelial cells in smoker changes to regular
cubodal cell
dysplasia
cells vary in size, shape and nucleus size/shape. less cell differentiation, precursor to cancer