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NUR 4010 Exam 3: Oncology Questions With Verified Answers

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NUR 4010 Exam 3: Oncology Questions With Verified Answers Signs and symptoms of cancer in childhood? Continued, unexplained weight loss Headaches, often with early morning vomiting Increased swelling or persistent pain in the bones, joints, back, or legs Lump or mass, especially in the abdomen, neck, chest, pelvis, or armpits Development of excessive bruising, bleeding, or rash Constant infections A whitish color behind the pupil Nausea that persists or vomiting without nausea Constant tiredness or noticeable paleness Eye or vision changes that occur suddenly and persist Recurring or persistent fevers of unknown origin Diagnostic tests and procedures for cancer? CBC Serum chemistries Liver function tests Coagulation studies Urinalysis Lumbar puncture (diagnostic and therapeutic) Bone marrow aspiration Bone marrow biopsy Chest X- Ray MRI CT PET MIBG Describe the mechanism of action for chemotherapy? Alkylating Agent: replace hydrogen atom of molecule by alkyl group - unbalanced growth of unaffected cell constituents and cell death Antimetabolites: inhibit further synthesis of DNA or RNA Plant Alkaloids: arrest cells in metaphase by binding microtubular protein needed for spindle formation Antitumor antibodies: natural products that interfere with cell division by reacting with DNA to prevent further replication of DNA and transcription of RNA What is a possible reaction that may occur with chemotherapy? Anaphalaxis - potentially fatal complication that may include angioedema, urticaria, flushing, rashes, bronchospasm, hypotension, nausea, vomiting How to treat chemotherapy anaphylaxis?

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NUR 4010 Exam 3: Oncology Questions With
Verified Answers
Signs and symptoms of cancer in childhood?
Continued, unexplained weight loss
Headaches, often with early morning vomiting
Increased swelling or persistent pain in the bones, joints, back, or legs
Lump or mass, especially in the abdomen, neck, chest, pelvis, or armpits
Development of excessive bruising, bleeding, or rash

Constant infections
A whitish color behind the pupil
Nausea that persists or vomiting without nausea
Constant tiredness or noticeable paleness
Eye or vision changes that occur suddenly and persist
Recurring or persistent fevers of unknown origin


Diagnostic tests and procedures for cancer?
CBC
Serum chemistries
Liver function tests
Coagulation studies
Urinalysis

Lumbar puncture (diagnostic and therapeutic)
Bone marrow aspiration
Bone marrow biopsy

Chest X- Ray
MRI
CT
PET
MIBG


Describe the mechanism of action for chemotherapy?
Alkylating Agent: replace hydrogen atom of molecule by alkyl group -> unbalanced growth of
unaffected cell constituents and cell death


Antimetabolites: inhibit further synthesis of DNA or RNA

Plant Alkaloids: arrest cells in metaphase by binding microtubular protein needed for spindle
formation

Antitumor antibodies: natural products that interfere with cell division by reacting with DNA to
prevent further replication of DNA and transcription of RNA


What is a possible reaction that may occur with chemotherapy?
Anaphalaxis - potentially fatal complication that may include angioedema, urticaria, flushing, rashes,
bronchospasm, hypotension, nausea, vomiting


How to treat chemotherapy anaphylaxis?

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