PATHOLOGIES QUESTIONS WITH
ANSWERS {GRADED A+}
What is neurulation? - ✔✔Neural tube formation
What is the gestational age of neurulation? - ✔✔3-4 weeks
What is an associated disorder if neurulation is disrupted? -
✔✔Myelominigocele
What is ventral induction? - ✔✔Formation of basic structures and brain
subdivision
What is the gestational age of ventral induction? - ✔✔5-6 weeks
What is an associated disorder if ventral induction is disrupted? -
✔✔Agenesis of corpus callosum
What is proliferation? - ✔✔Neural/glial cell formation and proliferation
What is the gestational age of proliferation? - ✔✔8-16 weeks
, What is an associated disorder if proliferation is disrupted? -
✔✔Macro/microcephaly
What is migration? - ✔✔Neurons move from ventricular/subventricular
zones to final destination
What is the gestational age of migration? - ✔✔12-20 weeks
What are some associated disorders if migration is disrupted? - ✔✔-
Lissencephaly
- General or focal seizures
- Schizencephaly
- Cerebral dysgenesis
What is organization? - ✔✔- Neurons differentiated and established
- Neurons aligned, layered, and oriented
- Axons/dendrites grow or selectively eliminated
What is the gestational age of organization? - ✔✔24 weeks - 3 years
What are some associated disorders if organization is disrupted? -
✔✔Associated with earlier developmental abnormalities and neural
network disorganization
What is myelination? - ✔✔Development of myelin around membrane
What is the gestational age of myelination? - ✔✔23 weeks - adulthood