Verified Solutions
CAP is the ___________ infectious ds in the US and the ______________
leading cause of death.
- Most deadly
- 8th
What normally prevents the development of lower respiratory tract infections
following aspiration of oropharyngeal secretions containing bacteria or
inhalation of infected aerosols?
Pulmonary defense mechanisms (cough reflex, mucociliary clearance system,
immune responses)
CAP occurs when _________________ .
There is a defect in 1 or more of the normal defense mechanisms (cough reflex,
mucociliary clearance system, immune responses) or when a large infectious
inoculum or a virulent pathogen overwhelms the immune response.
What bacterial pathogens cause CAP?
- Streptococcus pneumoniae (most common)
- Haemophilus influenzae
- Moraxella catarrhalis
What pathogen most commonly causes CAP in pts who
are immunocompetent?
Streptococcus pneumoniae
What pathogen(s) most commonly causes CAP in pts who have influenza?
Staph. aureus or Strept. pneumoniae
What pathogen(s) most commonly cause CAP in pts w/chronic alcoholism?
Klebsiella pneumoniae
What pathogen(s) most commonly cause CAP in pts who
have bronchiectasis or cystic fibrosis, or who have prolonged
hospitalizations?
Pseudomonas aeruginosa
What pathogen(s) most commonly cause CAP in pts who have exacerbation of
chronic bronchitis?
Moraxella catarrhalis
What pathogen(s) most commonly cause CAP in pts who are elderly,
have chronic lung ds, Sickle Cell ds, immunocompromised disorders, or who
are alcoholics or diabetic?
Haemophilus influenzae
What are some common viral causes of CAP?
- Influenza virus
- RSV
- Adenovirus
- Parainfluenza virus
What are some risk factors for developing CAP?
- Advanced age
- Alcoholism
- Tobacco use