WGU c785 Final Exam 2023 with all the
correct answers(Actual test 100% verified)
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the
outcome for their kids? - CORRECT ANSWER His daughters would be carriers.
This is x-link recessive.
Autosomal:
Dominant: - CORRECT ANSWER Autosomal: males and females equally
affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) - CORRECT ANSWER The process of copying
DNA in the lab. Uses Template DNA, Nucleotides (dNTPS), DNA Polymerase, and
DNA primers.
3 Steps of PCR - CORRECT ANSWER 1. Denaturation: DNA is heated to 95C to
separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to
copy and add DNA polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides
building a new DNA strand.
,Base Excision Repair (BER) - CORRECT ANSWER How you repair a mutation.
BER is used to repair damage to a base caused by harmful molecules. You
remove the base that is damaged and replace it. *BER removes a single
nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - CORRECT ANSWER replication. DNA
polymerase proofreads but sometimes a mismatch pair gets through. MMR
removes a large section of the nucleotides from the new DNA and DNA
polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? - CORRECT ANSWER
When a base is mismatched due to errors in replication. Such as G-T instead of
G-C. DNA polymerase comes by and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - CORRECT
ANSWER TRANSCRIPTION! DNA polymerase takes the individual nucleotides
and matches them to the parental sequences to ensure a correct pair. It must
bind with RNA primer to work.
What is needed for DNA replication? - CORRECT ANSWER DNA polymerase
Nonsense Mutation - CORRECT ANSWER Change in 1 nucleotide produces a
STOP codon Stop= nonsense because it is no more.
Silent Mutation - CORRECT ANSWER Change in 1 nucleotide but codes for the
same amino acid. Silent= the change doesn't change the name of the protein
, Missense Mutation - CORRECT ANSWER Change in 1 nucleotide leads to a code
for a different amino acid. Missense = mistake was made.
What happends during RNA splicing? - CORRECT ANSWER During RNA splicing
introns are cut out, the remaining exons are joined together.
5'ATG AGT CTC TCT 3'
Find the DNA template strand. - CORRECT ANSWER 3'TAC TCA GAG AGA 5'
The DNA template strand is complimentary. So start with the opposite number,
then go L-R with the complimentary letter.
5'ATG AGT CTC TCT 3'
What is the corresonding mRNA sequence? - CORRECT ANSWER 5'AUG AGU
CUC UCU 3'
This sequence is the same as the coding strand except T changes to U because it
is RNA. RNA doesn't have T.
How would a mutation from CTC to ATC affect the protein sequence? (CTC/ATC -
coding strand, AUC - mRNA strand) - CORRECT ANSWER This will make a
missense mutation because it changes the name of the protein. (look at the
chart provided.) missense = mistake
DNA replication process - CORRECT ANSWER DNA ->Transcription -> RNA ->
Translation -> Polypeptide
correct answers(Actual test 100% verified)
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the
outcome for their kids? - CORRECT ANSWER His daughters would be carriers.
This is x-link recessive.
Autosomal:
Dominant: - CORRECT ANSWER Autosomal: males and females equally
affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) - CORRECT ANSWER The process of copying
DNA in the lab. Uses Template DNA, Nucleotides (dNTPS), DNA Polymerase, and
DNA primers.
3 Steps of PCR - CORRECT ANSWER 1. Denaturation: DNA is heated to 95C to
separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to
copy and add DNA polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides
building a new DNA strand.
,Base Excision Repair (BER) - CORRECT ANSWER How you repair a mutation.
BER is used to repair damage to a base caused by harmful molecules. You
remove the base that is damaged and replace it. *BER removes a single
nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - CORRECT ANSWER replication. DNA
polymerase proofreads but sometimes a mismatch pair gets through. MMR
removes a large section of the nucleotides from the new DNA and DNA
polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? - CORRECT ANSWER
When a base is mismatched due to errors in replication. Such as G-T instead of
G-C. DNA polymerase comes by and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - CORRECT
ANSWER TRANSCRIPTION! DNA polymerase takes the individual nucleotides
and matches them to the parental sequences to ensure a correct pair. It must
bind with RNA primer to work.
What is needed for DNA replication? - CORRECT ANSWER DNA polymerase
Nonsense Mutation - CORRECT ANSWER Change in 1 nucleotide produces a
STOP codon Stop= nonsense because it is no more.
Silent Mutation - CORRECT ANSWER Change in 1 nucleotide but codes for the
same amino acid. Silent= the change doesn't change the name of the protein
, Missense Mutation - CORRECT ANSWER Change in 1 nucleotide leads to a code
for a different amino acid. Missense = mistake was made.
What happends during RNA splicing? - CORRECT ANSWER During RNA splicing
introns are cut out, the remaining exons are joined together.
5'ATG AGT CTC TCT 3'
Find the DNA template strand. - CORRECT ANSWER 3'TAC TCA GAG AGA 5'
The DNA template strand is complimentary. So start with the opposite number,
then go L-R with the complimentary letter.
5'ATG AGT CTC TCT 3'
What is the corresonding mRNA sequence? - CORRECT ANSWER 5'AUG AGU
CUC UCU 3'
This sequence is the same as the coding strand except T changes to U because it
is RNA. RNA doesn't have T.
How would a mutation from CTC to ATC affect the protein sequence? (CTC/ATC -
coding strand, AUC - mRNA strand) - CORRECT ANSWER This will make a
missense mutation because it changes the name of the protein. (look at the
chart provided.) missense = mistake
DNA replication process - CORRECT ANSWER DNA ->Transcription -> RNA ->
Translation -> Polypeptide
