HEMATOLOGY 2 STUDY GUIDE |LATEST
UPDATE {GRADED A+}
The qualitative hemoglobinopathies cause disease by producing
hemoglobin chains that are - ✔✔structurally altered
Which hemoglobinopathie is most common - ✔✔sickle cell
disease
What clinical feature of sickle cell disease accounts for the
highest number of hospital admissions - ✔✔vaso-occlusion
sickle cell disease is found in individuals descended from
ancestors from where - ✔✔Africa, Middle East, Mediterranean
What is an unusual finding in the blood smear of an adult with
sickle cell disease crisis - ✔✔heinz bodies
,What is the probable etiologic association between malaria and
sickle cell trait - ✔✔sickle gene offers some protection against
malaria
What would be unexpected in homozygous hemoglobin S -
✔✔hemoglobin A
A patient has target cells and a positive tube solubility test This
patient probably has - ✔✔sickle cell anemia or trait
Select the best test to confirm the diagnosis of a patient with
sickle cell anemia or trait - ✔✔hemoglobin electrophoresis
a patient has two bands on alkaline hemoglobin electrophoresis;
one lines up with hemoglobin A and the other is in the S position
what is the best course of action - ✔✔confirm sickle gene with
tube solubility test
Keeping the oxygen saturation low does not help the clinical
outcome of - ✔✔sickle cell anemia
a patient has 45% hemoglobin S, 55% hemoglobin A, and a
positive tube solubility. what is likely to be found - ✔✔normal
, blood smear and no disease or target cells on the blood smear
and no disease
Moderate to marked target cells are found on a blood smear What
can most likely be eliminated? - ✔✔hereditary spherocytosis
what would be an unexpected finding for patients with hgb SC
diseae or S/B 0- thalasemia - ✔✔normal tube solubility test
heniz bodies are found when hemoglobin - ✔✔precipitates
what is the correct relationship between red cells affinity for
oxygen and red cell production - ✔✔when affinity is high, less
oxygen is released and the body compensates by increasing
erythropoietin and making more red cells
Cellulose acetate is performed on a patient with known
homozygous hgb S who has recieved red cell transfusions in the
past week what hemoglobins would be expected to be found -
✔✔S,A, F and A2
UPDATE {GRADED A+}
The qualitative hemoglobinopathies cause disease by producing
hemoglobin chains that are - ✔✔structurally altered
Which hemoglobinopathie is most common - ✔✔sickle cell
disease
What clinical feature of sickle cell disease accounts for the
highest number of hospital admissions - ✔✔vaso-occlusion
sickle cell disease is found in individuals descended from
ancestors from where - ✔✔Africa, Middle East, Mediterranean
What is an unusual finding in the blood smear of an adult with
sickle cell disease crisis - ✔✔heinz bodies
,What is the probable etiologic association between malaria and
sickle cell trait - ✔✔sickle gene offers some protection against
malaria
What would be unexpected in homozygous hemoglobin S -
✔✔hemoglobin A
A patient has target cells and a positive tube solubility test This
patient probably has - ✔✔sickle cell anemia or trait
Select the best test to confirm the diagnosis of a patient with
sickle cell anemia or trait - ✔✔hemoglobin electrophoresis
a patient has two bands on alkaline hemoglobin electrophoresis;
one lines up with hemoglobin A and the other is in the S position
what is the best course of action - ✔✔confirm sickle gene with
tube solubility test
Keeping the oxygen saturation low does not help the clinical
outcome of - ✔✔sickle cell anemia
a patient has 45% hemoglobin S, 55% hemoglobin A, and a
positive tube solubility. what is likely to be found - ✔✔normal
, blood smear and no disease or target cells on the blood smear
and no disease
Moderate to marked target cells are found on a blood smear What
can most likely be eliminated? - ✔✔hereditary spherocytosis
what would be an unexpected finding for patients with hgb SC
diseae or S/B 0- thalasemia - ✔✔normal tube solubility test
heniz bodies are found when hemoglobin - ✔✔precipitates
what is the correct relationship between red cells affinity for
oxygen and red cell production - ✔✔when affinity is high, less
oxygen is released and the body compensates by increasing
erythropoietin and making more red cells
Cellulose acetate is performed on a patient with known
homozygous hgb S who has recieved red cell transfusions in the
past week what hemoglobins would be expected to be found -
✔✔S,A, F and A2
