NSG 6005 Week 2 Pharmacology Quiz with 100% Correct Answers

NSG 6005 Week 2 Pharmacology Quiz with 100% Correct Answers The major reason for not crushing a sustained release capsule is that, if crushed, the coated beads of the drugs could possibly result in: o Disintegration o Toxicity o Malabsorption o Deterioration - Answer- o Toxicity Drugs that have a significant first pass effect: o Must be given by enteral (oral) route only o Bypass the hepatic circulation o Are rapidly metabolized by the liver and may have little if any desired action o Are converted by the liver to more active in fat-soluble forms - Answer- o Are rapidly metabolized by the liver and may have little if any desired action When obtaining a drug history from Harold, he gives you a complete list of his prescription medications. He denies taking any other drugs, but you find that he occasionally takes aspirin for his arthritis flare-ups. This is an example of: o His appropriately only telling you about his regularly prescribed medications o His hiding information regarding his inappropriate use of aspirin from you o His common misconception that intermittently taking OTC medications are not an important part of his drug history o A common misuse of OTC aspirin - Answer- o His common misconception that intermittently taking OTC medications are not an important part of his drug history Drugs that use CYP3A4 isoenzymes for metabolism may: o Induce the metabolism of another drug o Inhibit the metabolism of another drug o Both A and B o Neither A nor B - Answer- o Both A and B A twenty four year old male received multiple fractures in a motor vehicle accident that required significant amounts of opioid medication to treat his pain. He is at risk for Type ____ ADR when he no longer requires the opioids. o A o C o E o G - Answer- o E Infants and young children are at higher risk of ADRs due to: o Immature renal function in schoolage children o Lack of safety and efficacy studies in the pediatric population o Children's skin being thicker than adults, requiring higher dosages of topical medication o Infant boys having a higher proportion of muscle mass, leading to a higher volume of distribution - Answer- o Lack of safety and efficacy studies in the pediatric population The type of ADR that is the result of an unwanted but otherwise normal pharmacological action of a drug given in the usual therapeutic dose is: o Type A o Type B o Type C o Type D - Answer- o Type A A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because: o Drugs given in liquid form are less irritating to the stomac