Immunology Exam 1 Questions With Verified
Answers
primary lymphoid organs
bone marrow and thymus
secondary lymphoid organs
lymph nodes, spleen, Peyer's patches
Hematopoietic stem cells are
multipotent stem cells
NK cells
secrete perforins and granzymes
NK cells release this for communication
cytokines
Innate immune cells
neutrophils, macrophages, DC cells, mast cells, eosinophils, basophils, NK cells
Adaptive immune cells
T cells and B cells
B cells and T cells contain which receptors
BCRs and TCRs respectively
Cytokines
Secreted by cells for communication
Chemokines
cytokine that helps movement, migration and enhancement of adaptive immunity
tumor necrosis factor
cytokine that promotes anti-tumor and inflammation
What is humoral immunity?
antibody-mediated immunity
What are the antibody isotypes
IgA, IgE, IgD, IgG, IgM
What are antibody idiotypes?
variable regions (Fab)
, What antibody isotype is found in mucosal immunity?
IgA
what antibody is most common
IgG
Which antibody is first released
IgM
What determine if BCRs are membrane bound or secreted as antibodies
mRNA splicing
PRRs are located on
innate immune cells
Toll-like receptors (TLRs)
plasma membrane PRRs for extracellular pathogens
NOD-like receptors (NLRs)
Cytoplasmic PRRs for intracellular pathogens
Endosomal TLRs
DNA/RNA pathogens
Neutrophils
phagocytes responsible for bacteria and some viruses
the most abundant WBC is
neutrophil
DC cells are
Phagocytes and antigen presenting cells
DC cells are located
in the blood and peripheral tissues
Macrophages
phagocytes located in tissues
Which cells are antigen presenting cells
B cells, macrophages, dendritic cells
Answers
primary lymphoid organs
bone marrow and thymus
secondary lymphoid organs
lymph nodes, spleen, Peyer's patches
Hematopoietic stem cells are
multipotent stem cells
NK cells
secrete perforins and granzymes
NK cells release this for communication
cytokines
Innate immune cells
neutrophils, macrophages, DC cells, mast cells, eosinophils, basophils, NK cells
Adaptive immune cells
T cells and B cells
B cells and T cells contain which receptors
BCRs and TCRs respectively
Cytokines
Secreted by cells for communication
Chemokines
cytokine that helps movement, migration and enhancement of adaptive immunity
tumor necrosis factor
cytokine that promotes anti-tumor and inflammation
What is humoral immunity?
antibody-mediated immunity
What are the antibody isotypes
IgA, IgE, IgD, IgG, IgM
What are antibody idiotypes?
variable regions (Fab)
, What antibody isotype is found in mucosal immunity?
IgA
what antibody is most common
IgG
Which antibody is first released
IgM
What determine if BCRs are membrane bound or secreted as antibodies
mRNA splicing
PRRs are located on
innate immune cells
Toll-like receptors (TLRs)
plasma membrane PRRs for extracellular pathogens
NOD-like receptors (NLRs)
Cytoplasmic PRRs for intracellular pathogens
Endosomal TLRs
DNA/RNA pathogens
Neutrophils
phagocytes responsible for bacteria and some viruses
the most abundant WBC is
neutrophil
DC cells are
Phagocytes and antigen presenting cells
DC cells are located
in the blood and peripheral tissues
Macrophages
phagocytes located in tissues
Which cells are antigen presenting cells
B cells, macrophages, dendritic cells
