Antibiotics - NAVLE -PP Questions And Answers.

Antibiotics - NAVLE -PP Questions And
Answers.
Beta-Lactam MOA -
\inhibits formation of petidoglycan cross-links of bacterial cell wall

Beta-Lactam Spectrum -
\G(+)
Limited G (-)
Anaerobes

Beta-Lactam

Cidal or Static -
\Cidal

Beta-Lactam

Time or Concentration -
\Time

Most common Beta-Lactams -
\Penicillin
Cephalosporin

Cephalosporin Spectrum -
\1st Gen: predominantly G(+)
2nd/3rd Gen: better Gr (-)

Cephalosporin

Cidal or static -
\cidal

Cephalosporin

Time or concentration -
\Time

Aminoglycocides MOA -
\Binds to 30s ribosomal subunit interfering with protein synthesis

Aminoglycocides

, Cidal or static -
\cidal

Aminoglycocides

Time or concentration -
\concentration

Aminoglycosides Spectrum -
\Gr (-)

Gentamicin and amikacin are examples of what antibiotic -
\Aminoglycosides

Fluoroquinolones MOA -
\Inhibit DNA gyrase necessary for bacterial DNA replication

Fluoroquinolones Spectrum -
\Gr (-)

Fluoroquinolones

Cidal or static -
\cidal

Fluoroquinolones

Time or concentration -
\concentration

Tetracyclines MOA -
\Binds to 30s ribosomal subunit thereby interfering with protein synthesis

Tetracyclines Spectrum -
\Gr (-)
Gr (-)
Anaerboes
Ehrlichial, Anaplasmal, Rickettsial

Tetracyclines

Cidal or static -
\static

Tetracyclines