update
Location of H4 receptors
eosinophils, neutrophils and T cells
second-generation antihistamine that cannot be removed by hemodialysis
cetirizine (hydrochloride) aka Zyrtec
diagnosis of enterobiasis
caused by small threadlike pinworm, Enterobius vermicularis, perianal cutaneous irritation, may result
in dermatitis and secondary bacterial infections. DIAGNOSIS: perianal swab using adhesive tape,
examined for eggs
treatment modalities of tuberculosis
directly observed therapy, adherence to drug regimen, important for anything less than daily doses,
highly susceptible to drug-drug interactions
according to universal prescribing alerts for ahminoglycosides, extended use increases risk for
infection by which pathogens
C.difficile-associated diarrhea and pseudomembranous colitis with extended use
mode of administration of dactinomycin
vesicants, should be administered only by intravenous route to prevent extravasation. If extravasation
occurs administration should be stopped, monitor for signs of infection & bleeding. Myelosuppression
FDA- approved indication for methotrexate
meningeal leukemia, trophoblastic neoplasms. Breast Cancer
Synthetic muscarinic receptor antagonist that possesses M3 receptor selectivity
darifenacin & solifenacin
Autonomic agents associated simulation of insulin production, increase glycogenolysis in the liver and
complicate the management of diabetes mellitus
may stimulate insulin production- increase glycogenolysis in the liver and complicate the
management--sympathomimetic autonomic agents
most commonly used therapy for iron-deficiency anemia
ferrous sulfate
fatalities have occurred with the test dose of which drug
iron dextran
antilipemic agent that targets triglycerides
Fibrates
, mechanism of action calcium-channel blocking agents
act on calcium channels in large vessels to produce vasodilation and subsequent reduction in blood
pressure
clevidipine
used as an intravenous drug for hypertensive emergencies due to it's rapid onset of action and short
half-life
hypotensive agent FDA-approved for the treatment of ADHD
Guanfacine (extended release) - alpha 2 receptor agonist
when prescribing benzodiazepines, only lorazepam, diazepam, or temazepam should be considered
for which patients
patients with hepatic impairment
indication for lithium
mood stabilizer--Mania, or depressive symptoms in bipolar disorder
important consideration when administering total parenteral nutrition peripherally
can cause phlebitis in peripheral line, lower osmolarity is necessary
mechanism of action of thiazide like diuretics
work in the distal tubule
In asthma patients, bronchospasms occur when an irritant interacts with:
Arachidonic acid
Which of the following statements correctly describes hydromorphone?
It is more potent and has lower dosages requirements than morphine
Drug acts as a tyrosine kinase inhibitor
Nintedanib
Which of the following is true regarding proper technique and precautions for the administration of
eye drops
all of the above: administration one drop at a time, use a solution before using a suspension, more
than one drop at a time can cause the eye to tear in an attempt to flush out the extra fluid, which will
make the medication less effective
Choose the correct statement describing pilocarpine?
It acts on the ciliary muscle
Which of the following mydriatic drugs is associated with increased risk for seizures?
Cyclopentolate