HESI PHARMACOLOGY EXIT EXAM LATEST
2022-2023 REAL EXAM QUESTIONS / 2022-2023
PHARMACOLOGY HESI EXIT EXAM REAL
EXAM WITH ANSWERS | GUARANTEED A
VERSION 1
1) A nurse is caring for a client with hyperparathyroidism and notes that the client's serum
calcium level is 13 mg/dL. Which medication should the nurse prepare to administer as
prescribed to the client?
1. Calcium chloride
2. Calcium gluconate
3. Calcitonin (Miacalcin)
4. Large doses of vitamin D 3. Calcitonin (Miacalcin)
Rationale:
The normal serum calcium level is 8.6 to 10.0 mg/dL. This client is experiencing hypercalcemia.
Calcium gluconate and calcium chloride are medications used for the treatment of tetany, which
occurs as a result of acute hypocalcemia. In hypercalcemia, large doses of vitamin D need to be
avoided. Calcitonin, a thyroid hormone, decreases the plasma calcium level by inhibiting bone
resorption and lowering the serum calcium concentration.
2.) Salicylic acid is prescribed for a client with a diagnosis of psoriasis. The nurse monitors the
client, knowing that which of the following would indicate the presence of systemic toxicity from
this medication?
1. Tinnitus
2. Diarrhea
3. Constipation
4. Decreased respirations 1. Tinnitus
Rationale:
Salicylic acid is absorbed readily through the skin, and systemic toxicity (salicylism) can result.
Symptoms include tinnitus, dizziness, hyperpnea, and psychological disturbances. Constipation
and diarrhea are not associated with salicylism.
1
,4.) The camp nurse asks the children preparing to swim in the lake if they have applied
sunscreen. The nurse reminds the children that chemical sunscreens are most effective when
applied:
1. Immediately before swimming
2. 15 minutes before exposure to the sun
3. Immediately before exposure to the sun
4. At least 30 minutes before exposure to the sun 4. At least 30 minutes before exposure
to the sun
Rationale:
Sunscreens are most effective when applied at least 30 minutes before exposure to the sun so
that they can penetrate the skin. All sunscreens should be reapplied after swimming or sweating.
5.) Mafenide acetate (Sulfamylon) is prescribed for the client with a burn injury.
When applying the medication, the client complains of local discomfort and burning. Which of the
following is the most appropriate nursing action?
1. Notifying the registered nurse
2. Discontinuing the medication
3. Informing the client that this is normal
4. Applying a thinner film than prescribed to the burn site 3. Informing the client that this
is normal
Rationale:
Mafenide acetate is bacteriostatic for gram-negative and gram-positive organisms and is used
to treat burns to reduce bacteria present in avascular tissues. The client should be informed
that the medication will cause local discomfort and burning and that this is a normal reaction;
therefore options 1, 2, and 4 are incorrect
6.) The burn client is receiving treatments of topical mafenide acetate (Sulfamylon) to the site
of injury. The nurse monitors the client, knowing that which of the following indicates that a
systemic effect has occurred?
1.Hyperventilation
2.Elevated blood pressure
3.Local pain at the burn site
4.Local rash at the burn site 1.Hyperventilation
Rationale:
Mafenide acetate is a carbonic anhydrase inhibitor and can suppress renal excretion of acid,
thereby causing acidosis. Clients receiving this treatment should be monitored for signs of an
acid-base imbalance (hyperventilation). If this occurs, the medication should be discontinued for
1 to 2 days. Options 3 and 4 describe local rather than systemic effects. An elevated blood
pressure may be expected from the pain that occurs with a burn injury.
7.) Isotretinoin is prescribed for a client with severe acne. Before the administration of this
medication, the nurse anticipates that which laboratory test will be prescribed?
2
,1. Platelet count
2. Triglyceride level
3. Complete blood count
4. White blood cell count 2. Triglyceride level
Rationale:
Isotretinoin can elevate triglyceride levels. Blood triglyceride levels should be measured
before treatment and periodically thereafter until the effect on the triglycerides has been
evaluated. Options 1, 3, and 4 do not need to be monitored specifically during this treatment.
8.) A client with severe acne is seen in the clinic and the health care provider (HCP) prescribes
isotretinoin. The nurse reviews the client's medication record and would contact the (HCP) if
the client is taking which medication?
1. Vitamin A
2. Digoxin (Lanoxin)
3. Furosemide (Lasix)
4. Phenytoin (Dilantin) 1. Vitamin A
Rationale:
Isotretinoin is a metabolite of vitamin A and can produce generalized intensification of
isotretinoin toxicity. Because of the potential for increased toxicity, vitamin A supplements
should be discontinued before isotretinoin therapy. Options 2, 3, and 4 are not contraindicated
with the use of isotretinoin.
9.) The nurse is applying a topical corticosteroid to a client with eczema. The nurse would
monitor for the potential for increased systemic absorption of the medication if the medication
were being applied to which of the following body areas?
1. Back
2. Axilla
3. Soles of the feet
4. Palms of the hands 2. Axilla
Rationale:
Topical corticosteroids can be absorbed into the systemic circulation. Absorption is higher from
regions where the skin is especially permeable (scalp, axilla, face, eyelids, neck, perineum,
genitalia), and lower from regions in which permeability is poor (back, palms, soles).
10.) The clinic nurse is performing an admission assessment on a client. The nurse notes that
the client is taking azelaic acid (Azelex). Because of the medication prescription, the nurse
would suspect that the client is being treated for:
1. Acne
2. Eczema
3. Hair loss
4. Herpes simplex 1. Acne
3
, Rationale:
Azelaic acid is a topical medication used to treat mild to moderate acne. The acid appears to
work by suppressing the growth of Propionibacterium acnes and decreasing the proliferation of
keratinocytes. Options 2, 3, and 4 are incorrect.
11.) The health care provider has prescribed silver sulfadiazine (Silvadene) for the client with
a partial-thickness burn, which has cultured positive for gram-negative bacteria. The nurse
is reinforcing information to the client about the medication. Which statement made by the
client indicates a lack of understanding about the treatments?
1. "The medication is an antibacterial."
2. "The medication will help heal theburn."
3. "The medication will permanently stain my skin."
4. "The medication should be applied directly to the wound." 3. "The medication will
permanently stain my skin."
Rationale:
Silver sulfadiazine (Silvadene) is an antibacterial that has a broad spectrum of activity against
gram-negative bacteria, gram-positive bacteria, and yeast. It is applied directly to the wound to
assist in healing. It does not stain the skin.
12.) A nurse is caring for a client who is receiving an intravenous (IV) infusion of an
antineoplastic medication. During the infusion, the client complains of pain at the insertion site.
During an inspection of the site, the nurse notes redness and swelling and that the rate of
infusion of the medication has slowed. The nurse should take which appropriate action?
1. Notify the registered nurse.
2. Administer pain medication to reduce the discomfort.
3. Apply ice and maintain the infusion rate, as prescribed.
4. Elevate the extremity of the IV site, and slow the infusion. 1. Notify the registered
nurse.
Rationale:
When antineoplastic medications (Chemotheraputic Agents) are administered via IV, great care
must be taken to prevent the medication from escaping into the tissues surrounding the
injection site, because pain, tissue damage, and necrosis can result. The nurse monitors for
signs of extravasation, such as redness or swelling at the insertion site and a decreased infusion
rate. If extravasation occurs, the registered nurse needs to be notified; he or she will then
contact the health care provider.
13.) The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously.
The nurse caring for the client anticipates that which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies 4. Pulmonary function studies
Rationale:
4
2022-2023 REAL EXAM QUESTIONS / 2022-2023
PHARMACOLOGY HESI EXIT EXAM REAL
EXAM WITH ANSWERS | GUARANTEED A
VERSION 1
1) A nurse is caring for a client with hyperparathyroidism and notes that the client's serum
calcium level is 13 mg/dL. Which medication should the nurse prepare to administer as
prescribed to the client?
1. Calcium chloride
2. Calcium gluconate
3. Calcitonin (Miacalcin)
4. Large doses of vitamin D 3. Calcitonin (Miacalcin)
Rationale:
The normal serum calcium level is 8.6 to 10.0 mg/dL. This client is experiencing hypercalcemia.
Calcium gluconate and calcium chloride are medications used for the treatment of tetany, which
occurs as a result of acute hypocalcemia. In hypercalcemia, large doses of vitamin D need to be
avoided. Calcitonin, a thyroid hormone, decreases the plasma calcium level by inhibiting bone
resorption and lowering the serum calcium concentration.
2.) Salicylic acid is prescribed for a client with a diagnosis of psoriasis. The nurse monitors the
client, knowing that which of the following would indicate the presence of systemic toxicity from
this medication?
1. Tinnitus
2. Diarrhea
3. Constipation
4. Decreased respirations 1. Tinnitus
Rationale:
Salicylic acid is absorbed readily through the skin, and systemic toxicity (salicylism) can result.
Symptoms include tinnitus, dizziness, hyperpnea, and psychological disturbances. Constipation
and diarrhea are not associated with salicylism.
1
,4.) The camp nurse asks the children preparing to swim in the lake if they have applied
sunscreen. The nurse reminds the children that chemical sunscreens are most effective when
applied:
1. Immediately before swimming
2. 15 minutes before exposure to the sun
3. Immediately before exposure to the sun
4. At least 30 minutes before exposure to the sun 4. At least 30 minutes before exposure
to the sun
Rationale:
Sunscreens are most effective when applied at least 30 minutes before exposure to the sun so
that they can penetrate the skin. All sunscreens should be reapplied after swimming or sweating.
5.) Mafenide acetate (Sulfamylon) is prescribed for the client with a burn injury.
When applying the medication, the client complains of local discomfort and burning. Which of the
following is the most appropriate nursing action?
1. Notifying the registered nurse
2. Discontinuing the medication
3. Informing the client that this is normal
4. Applying a thinner film than prescribed to the burn site 3. Informing the client that this
is normal
Rationale:
Mafenide acetate is bacteriostatic for gram-negative and gram-positive organisms and is used
to treat burns to reduce bacteria present in avascular tissues. The client should be informed
that the medication will cause local discomfort and burning and that this is a normal reaction;
therefore options 1, 2, and 4 are incorrect
6.) The burn client is receiving treatments of topical mafenide acetate (Sulfamylon) to the site
of injury. The nurse monitors the client, knowing that which of the following indicates that a
systemic effect has occurred?
1.Hyperventilation
2.Elevated blood pressure
3.Local pain at the burn site
4.Local rash at the burn site 1.Hyperventilation
Rationale:
Mafenide acetate is a carbonic anhydrase inhibitor and can suppress renal excretion of acid,
thereby causing acidosis. Clients receiving this treatment should be monitored for signs of an
acid-base imbalance (hyperventilation). If this occurs, the medication should be discontinued for
1 to 2 days. Options 3 and 4 describe local rather than systemic effects. An elevated blood
pressure may be expected from the pain that occurs with a burn injury.
7.) Isotretinoin is prescribed for a client with severe acne. Before the administration of this
medication, the nurse anticipates that which laboratory test will be prescribed?
2
,1. Platelet count
2. Triglyceride level
3. Complete blood count
4. White blood cell count 2. Triglyceride level
Rationale:
Isotretinoin can elevate triglyceride levels. Blood triglyceride levels should be measured
before treatment and periodically thereafter until the effect on the triglycerides has been
evaluated. Options 1, 3, and 4 do not need to be monitored specifically during this treatment.
8.) A client with severe acne is seen in the clinic and the health care provider (HCP) prescribes
isotretinoin. The nurse reviews the client's medication record and would contact the (HCP) if
the client is taking which medication?
1. Vitamin A
2. Digoxin (Lanoxin)
3. Furosemide (Lasix)
4. Phenytoin (Dilantin) 1. Vitamin A
Rationale:
Isotretinoin is a metabolite of vitamin A and can produce generalized intensification of
isotretinoin toxicity. Because of the potential for increased toxicity, vitamin A supplements
should be discontinued before isotretinoin therapy. Options 2, 3, and 4 are not contraindicated
with the use of isotretinoin.
9.) The nurse is applying a topical corticosteroid to a client with eczema. The nurse would
monitor for the potential for increased systemic absorption of the medication if the medication
were being applied to which of the following body areas?
1. Back
2. Axilla
3. Soles of the feet
4. Palms of the hands 2. Axilla
Rationale:
Topical corticosteroids can be absorbed into the systemic circulation. Absorption is higher from
regions where the skin is especially permeable (scalp, axilla, face, eyelids, neck, perineum,
genitalia), and lower from regions in which permeability is poor (back, palms, soles).
10.) The clinic nurse is performing an admission assessment on a client. The nurse notes that
the client is taking azelaic acid (Azelex). Because of the medication prescription, the nurse
would suspect that the client is being treated for:
1. Acne
2. Eczema
3. Hair loss
4. Herpes simplex 1. Acne
3
, Rationale:
Azelaic acid is a topical medication used to treat mild to moderate acne. The acid appears to
work by suppressing the growth of Propionibacterium acnes and decreasing the proliferation of
keratinocytes. Options 2, 3, and 4 are incorrect.
11.) The health care provider has prescribed silver sulfadiazine (Silvadene) for the client with
a partial-thickness burn, which has cultured positive for gram-negative bacteria. The nurse
is reinforcing information to the client about the medication. Which statement made by the
client indicates a lack of understanding about the treatments?
1. "The medication is an antibacterial."
2. "The medication will help heal theburn."
3. "The medication will permanently stain my skin."
4. "The medication should be applied directly to the wound." 3. "The medication will
permanently stain my skin."
Rationale:
Silver sulfadiazine (Silvadene) is an antibacterial that has a broad spectrum of activity against
gram-negative bacteria, gram-positive bacteria, and yeast. It is applied directly to the wound to
assist in healing. It does not stain the skin.
12.) A nurse is caring for a client who is receiving an intravenous (IV) infusion of an
antineoplastic medication. During the infusion, the client complains of pain at the insertion site.
During an inspection of the site, the nurse notes redness and swelling and that the rate of
infusion of the medication has slowed. The nurse should take which appropriate action?
1. Notify the registered nurse.
2. Administer pain medication to reduce the discomfort.
3. Apply ice and maintain the infusion rate, as prescribed.
4. Elevate the extremity of the IV site, and slow the infusion. 1. Notify the registered
nurse.
Rationale:
When antineoplastic medications (Chemotheraputic Agents) are administered via IV, great care
must be taken to prevent the medication from escaping into the tissues surrounding the
injection site, because pain, tissue damage, and necrosis can result. The nurse monitors for
signs of extravasation, such as redness or swelling at the insertion site and a decreased infusion
rate. If extravasation occurs, the registered nurse needs to be notified; he or she will then
contact the health care provider.
13.) The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously.
The nurse caring for the client anticipates that which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies 4. Pulmonary function studies
Rationale:
4
