TREATMENT MODALITIES) WITH
COMPLETE QUESTIONS AND ANSWERS
{ GRADED A+}
A patient demonstrates an adequate understanding of the teaching
provided regarding chemotherapy and myelosuppression by stating:
"Myelosuppression is:
a potential side effect of many cancer treatments."
unintentional prior to a bone marrow transplant."
when laboratory values show an elevation in the white blood cell count."
the overreaction of the body's immune system to a medication." - ✔✔a
potential side effect of many cancer treatments."
,Answer: Chemotherapy will decrease the response by the immune system
by causing neutropenia, anemia, and thrombocytopenia, collectively known
as myelosuppression.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014).
Chemotherapy and biotherapy guidelines and recommendations for
practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 171.
Alkylating agents exert their effects by:
binding to DNA strands, preventing DNA replication and cell division.
causing the release of toxic free radicals inside the cell, triggering cell
apoptosis.
attaching to CD52 on the surface of B and T cells, resulting in antibody-
dependent lysis.
disrupting folate-dependent metabolic processes essential for cell
replication. - ✔✔binding to DNA strands, preventing DNA replication and
cell division.
Answer: Alkalyting agents break the DNA helix strand and interfere with
DNA replication.
, Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014).
Chemotherapy and biotherapy guidelines and recommendations for
practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 27(t).
The nurse preparing to instill intravesical mitomycin should wear which of
the following pieces of personal protective equipment?
A plastic face shield
A pair of shoe covers
A front-closing laboratory gown
One pair of powdered nitrile gloves - ✔✔A plastic face shield
Answer: A plastic face shield should be used when splashing of hazardous
drugs is possible. Intravesical administration carries a risk of splashing.
Reference: Polovich, M. (2017). Safe handling of hazardous drugs (3rd
ed.). Pittsburgh, PA: Oncology Nursing Society, p. 27.
Adjuvant therapy for breast cancer is administered: