QUESTIONS WITH COMPLETE
ANSWERS { GRADED A+}
How does carbamazepine work? - ✔✔Works by decreasing nerve
impulses that cause seizures and pain
How often should carbamazepine lab values be monitored? What labs? -
✔✔CBC q 3-4 months
What anti-seizure med auto induces metabolism? - ✔✔Carbamazepine
What medication decreases the production of RBCs, WBCs, and
platelets? - ✔✔Carbamazepine
What is carbamazepine half-life? - ✔✔Single dose: 30 hours
Multiple dose: 15 hours
,What is a great risk of seizure potential while taking anti-seizure
medications? - ✔✔Stopping the medication abruptly.
What type of medication is topiramate (Topamax)? - ✔✔Anti-seizure
med
What does topiramate cause? - ✔✔Electrolyte imbalance --
hyperchloremic metabolic acidosis
What are adverse effects of topiramate? - ✔✔Weight loss, high
temperature, and inability to sweat
What medication affects Lamictal? - ✔✔OCPs decrease the effects of
this drug, so the dose must be doubled
Can valproate (Depakote) be used during pregnancy? - ✔✔It is a
known teratogen. If needed, must be used after 1st trimester.
What must be ruled out in patients before starting an anti-depressant? -
✔✔hypothyroidism
, Anti-depressant that is to be used with caution in cardiac patients due to
behaving like class 1 anti-arrythmics? - ✔✔TCAs
TCA side effects are mainly of what type? - ✔✔Anti-cholinergic
What is a first-line antidepressant in children? - ✔✔fluoxetine (Prozac)
How do you discontinue an SSRI? - ✔✔Taper by reducing the dose by
50% for 3-4 days
When are MAOIs effective? - ✔✔In atypical depression or Parkinson's
Why are MAOIs reserved for last line of treatment? - ✔✔Lethal drug
interactions and food interactions
How long before starting a new antidepressant after MAOIs? - ✔✔At
least 2 weeks to clear it from system
What are high tyramine foods and when are they contraindicated? -
✔✔Fermented foods; aged cheese, wine alcohol
Contraindicated with MAOI use