Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch)
1. A patient suspected of having Cushing’s disease comes to the clinic. What drug
might the nurse administer to test for adrenal function and responsiveness?
a. Corticotropin
b. Menotropins
c. Thyrotropin alfa
d. Chorionic gonadotropin
Ans: A
Feedback:
Corticotropin (ACTH) and cosyntropin are used for diagnostic purposes to test
adrenal function and responsiveness. Menotropin is a purified preparation of
gonadotropins and is used as a fertility drug. Thyrotropin alfa is used as adjunctive
treatment for radioiodine ablation of thyroid tissue remnants in patients who have
undergone a near-total to total thyroidectomy for well-differentiated thyroid cancer
and who do not have evidence of metastatic thyroid cancer. Chorionic gonadotropin
acts like luteinizing hormone and stimulates the production of testosterone and
progesterone.
2. A nurse is working at a fertility clinic. Today she is administering ganirelix acetate
(Antagon) to a woman participating in a fertility research program. By what route
is this drug administered?
a. Orally
b. Subcutaneously
c. Intramuscularly
d. IV
Ans: B
Feedback:
Ganirelix acetate (Antagon) is administered subcutaneously and cannot be
administered orally, intramuscularly, or intravenously.
3. A patient is taking leuprolide (Lupron) to treat prostatic cancer. The nurse caring
for this patient is careful to monitor for what?
a. Diarrhea
b. Urinary retention
c. Peripheral edema
d. Increased appetite
, Ans: C
Feedback:
Peripheral edema is an identified adverse effect of leuprolide therapy. Constipation
not diarrhea; urinary frequency not urinary retention; and anorexia not increased
appetite are also identified adverse effects.
4. After administering somatropin (Saizen) to an 11-year-old patient with growth
failure, what outcome would indicate that the drug should be stopped?
a. Early sexual development
b. Thyroid overactivity
c. Closure of the epiphyses in long bones
d. Gynecomastia
Ans: C
Feedback:
Closure of the epiphyses is a sign that the drug should be stopped. Early sexual
development, thyroid overactivity, and gynecomastia would not be associated with
this drug.
5. The nurse administers desmopressin (DDAVP) to the patient to treat diabetes
insipidus. What assessment finding would indicate to the nurse that the
desmopressin is producing a therapeutic effect?
a. Decreased urine output
b. Decreased water reabsorption
c. Increased plasma osmolarity
d. Decreased blood volume
Ans: A
Feedback:
Desmopressin produces its antidiuretic activity in the kidneys, causing the cortical and
medullary parts of the collecting duct to become permeable to water, thereby
increasing water reabsorption and decreasing urine formation. These activities reduce
plasma osmolarity and increase blood volume.
6. A patient with diabetes insipidus is taking desmopressin (DDAVP). He or she is
complaining of drowsiness, lightheadedness, and headache. What does the nurse
suspect that he is experiencing?
a. An allergic reaction
b. Dehydration
c. Depression
d. Water intoxication
Ans: D
1. A patient suspected of having Cushing’s disease comes to the clinic. What drug
might the nurse administer to test for adrenal function and responsiveness?
a. Corticotropin
b. Menotropins
c. Thyrotropin alfa
d. Chorionic gonadotropin
Ans: A
Feedback:
Corticotropin (ACTH) and cosyntropin are used for diagnostic purposes to test
adrenal function and responsiveness. Menotropin is a purified preparation of
gonadotropins and is used as a fertility drug. Thyrotropin alfa is used as adjunctive
treatment for radioiodine ablation of thyroid tissue remnants in patients who have
undergone a near-total to total thyroidectomy for well-differentiated thyroid cancer
and who do not have evidence of metastatic thyroid cancer. Chorionic gonadotropin
acts like luteinizing hormone and stimulates the production of testosterone and
progesterone.
2. A nurse is working at a fertility clinic. Today she is administering ganirelix acetate
(Antagon) to a woman participating in a fertility research program. By what route
is this drug administered?
a. Orally
b. Subcutaneously
c. Intramuscularly
d. IV
Ans: B
Feedback:
Ganirelix acetate (Antagon) is administered subcutaneously and cannot be
administered orally, intramuscularly, or intravenously.
3. A patient is taking leuprolide (Lupron) to treat prostatic cancer. The nurse caring
for this patient is careful to monitor for what?
a. Diarrhea
b. Urinary retention
c. Peripheral edema
d. Increased appetite
, Ans: C
Feedback:
Peripheral edema is an identified adverse effect of leuprolide therapy. Constipation
not diarrhea; urinary frequency not urinary retention; and anorexia not increased
appetite are also identified adverse effects.
4. After administering somatropin (Saizen) to an 11-year-old patient with growth
failure, what outcome would indicate that the drug should be stopped?
a. Early sexual development
b. Thyroid overactivity
c. Closure of the epiphyses in long bones
d. Gynecomastia
Ans: C
Feedback:
Closure of the epiphyses is a sign that the drug should be stopped. Early sexual
development, thyroid overactivity, and gynecomastia would not be associated with
this drug.
5. The nurse administers desmopressin (DDAVP) to the patient to treat diabetes
insipidus. What assessment finding would indicate to the nurse that the
desmopressin is producing a therapeutic effect?
a. Decreased urine output
b. Decreased water reabsorption
c. Increased plasma osmolarity
d. Decreased blood volume
Ans: A
Feedback:
Desmopressin produces its antidiuretic activity in the kidneys, causing the cortical and
medullary parts of the collecting duct to become permeable to water, thereby
increasing water reabsorption and decreasing urine formation. These activities reduce
plasma osmolarity and increase blood volume.
6. A patient with diabetes insipidus is taking desmopressin (DDAVP). He or she is
complaining of drowsiness, lightheadedness, and headache. What does the nurse
suspect that he is experiencing?
a. An allergic reaction
b. Dehydration
c. Depression
d. Water intoxication
Ans: D
