Pharmacology: Medications | Exam Review
What is the percent solution of racemic epinephrine? ** Answ ** 2.25%
Name some examples of catecholamines: ** Answ ** Epinephrine
norepinephrine
racemic epinephrine
dopamine
isoproterenol
lisoetharine
bitolterol
Why can catecholamines not be give orally? ** Answ ** They are degraded in the GI tract
where MAO is found.
Name some examples of resorcinols: ** Answ ** Metaproterenol
Terbutaline
Metaproterenol ** Answ ** *Resorcinol* (beta-agonist), only available as a tablet or syrup.
More B2-specific, because more bulky side chain, but substantial cardiac side effects.
Metaproterenol dose ** Answ ** 20mg
Terbutaline ** Answ ** *Resorcinol* (beta-agonist), B2-specific with very little cardiac
effects. Available in parental form to treat bronchospasm or to stop premature labor.
What is the trade name of Albuterol? ** Answ ** Proventil HFA
Ventolin HFA
Albuterol is the _______ name. ** Answ ** generic
Albuterol ** Answ ** *Saligenin* (beta-agonist), very B2-specific very few side effects
because of its long side chain. Available as a syrup for children, oral tablets, extended-release
tablets, nebulizer solution, MDI, and DPI.
, Albuterol dose ** Answ ** 0.5mL equals 2.5mg
*1mL equals 5mg*
1.5mL equals 7.5mg
2mL equals 10mg
What is the percent solution of Albuterol? ** Answ ** 0.5%
What is the trade name of Pirbuterol? ** Answ ** Maxair Autohaler
Pirbuterol ** Answ ** *Saligenin* (beta-agonist), slight modification to the nucleus, but it has
the same side chain as albuterol. Available orally, as a syrup for pediatric patients, and as an
MDI with a breath-actuated inhaler device.
What is the trade name of Levalbuterol? ** Answ ** Xopenex
Levalbuterol ** Answ ** *Saligenin* (beta-agonist), R-isomer that appears to have little
clinically significant advantage over Albuterol.
What is the trade name of Salmeterol? ** Answ ** Servent
Salmeterol ** Answ ** *Saligenin* (beta-agonist), lipophlilic, provides a prolonged duration of
action, ideal for maintenance, but it cannot be used as a rescue treatment because of its very slow
onset
What is the trade name of Formoterol? ** Answ ** Perforomist
Foradil
Formoterol ** Answ ** *Saligenin* (beta-agonist), fast and long-acting, used as a maintenance
drug in the treatment of asthma in adults and children. Available in DPI using the aerolizer
inhaler or as a solution that can be nebulized. Not recommended as a rescue drug.
Formoterol dose ** Answ ** 12mcg (capsule)
20mcg (nebulized)
What is the trade name of Arformoterol? ** Answ ** Brovana
Arformoterol ** Answ ** *Saligenin* (beta-agonist), long-acting indicated for the treatment of
COPD.
Arformoterol dose ** Answ ** 15mg (nebulized)