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BASIC PRINCIPLES OF PHARMACOLOGY

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This document provides an in-depth overview of the fundamental principles of pharmacology, serving as an essential guide for students, healthcare professionals, and anyone interested in the science of drugs. It covers key concepts and processes that underpin the study of pharmacology, ensuring a solid foundation in understanding how drugs interact with biological systems.

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A. DEFINITION OF TERMS

B. BRANCHES OF PHARMACOLOGY

C. CLASSIFICATIONS OF DRUGS

D. PHARMACODYNAMIC PRINCIPLES

E. PHARMACOKINETIC PRINCIPLES




➢ study of drugs
➢ biological and physiologic aspects of drug effects, including ADME, PHARMACODYNAMICS
toxicity, and specific MOA of drugs
➢ “what drugs do to the body”
➢ substance that affects a biological system in a potentially useful way ➢ mechanism of action of drugs (MOA)
➢ Any agent that has the ability to modify (alter) the body structure and
function
➢ agents used in the medication, diagnosis, prevention, treatment and cure
of disease in man or other animals (USP) PHARMACOKINETICS
➢ “what the body (katawan) does to drugs”
➢ any chemical agent that produces harmful effect
(eg. Arsenic or Lead) ➢ Absorption, Distribution, Metabolism, Excretion
➢ NOTE: Drugs in high concentrations become poisons.

➢ poison of biological origin
(tetrodotoxin)

, PHARMACOTHERAPEUTICS
PHARMACOGENETICS
➢ defined as the study of the rational drug use in the
➢ genetic influences on responses to drugs
management of diseases


PHARMACOGENOMICS
PHARMACEUTICS ➢ branch of pharmacogenetics
➢ “what the pharmacists drugs do to the drugs” ➢ the relation of the individual’s genetic makeup to his or
➢ involves preparation of dosage forms of drugs her response to specific drugs, as an important part of
therapeutics




PHARMACOEPIDEMIOLOGY
➢ study of drugs effects at a population level • Functional Modifiers

PHARMACOECONOMICS • Replenishers
➢ branch of health economics
➢ quantify the cost and benefit of drugs used • Diagnostic Agents
therapeutically
• Chemotherapeutic Agents
PHARMACOTOXICOLOGY
➢ deals with the study of adverse effects of drugs
➢ mechanism of toxicity (MOT)

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Uploaded on
June 22, 2024
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Written in
2023/2024
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