B. BRANCHES OF PHARMACOLOGY
C. CLASSIFICATIONS OF DRUGS
D. PHARMACODYNAMIC PRINCIPLES
E. PHARMACOKINETIC PRINCIPLES
➢ study of drugs
➢ biological and physiologic aspects of drug effects, including ADME, PHARMACODYNAMICS
toxicity, and specific MOA of drugs
➢ “what drugs do to the body”
➢ substance that affects a biological system in a potentially useful way ➢ mechanism of action of drugs (MOA)
➢ Any agent that has the ability to modify (alter) the body structure and
function
➢ agents used in the medication, diagnosis, prevention, treatment and cure
of disease in man or other animals (USP) PHARMACOKINETICS
➢ “what the body (katawan) does to drugs”
➢ any chemical agent that produces harmful effect
(eg. Arsenic or Lead) ➢ Absorption, Distribution, Metabolism, Excretion
➢ NOTE: Drugs in high concentrations become poisons.
➢ poison of biological origin
(tetrodotoxin)
, PHARMACOTHERAPEUTICS
PHARMACOGENETICS
➢ defined as the study of the rational drug use in the
➢ genetic influences on responses to drugs
management of diseases
PHARMACOGENOMICS
PHARMACEUTICS ➢ branch of pharmacogenetics
➢ “what the pharmacists drugs do to the drugs” ➢ the relation of the individual’s genetic makeup to his or
➢ involves preparation of dosage forms of drugs her response to specific drugs, as an important part of
therapeutics
PHARMACOEPIDEMIOLOGY
➢ study of drugs effects at a population level • Functional Modifiers
PHARMACOECONOMICS • Replenishers
➢ branch of health economics
➢ quantify the cost and benefit of drugs used • Diagnostic Agents
therapeutically
• Chemotherapeutic Agents
PHARMACOTOXICOLOGY
➢ deals with the study of adverse effects of drugs
➢ mechanism of toxicity (MOT)