NU664CX A+Questions and Answers 100%
Verified
Know the route of administration for newer agent asenapine (Saphris) and what
instructions should be given to the patient regarding administration. - ANS-a. Orally
disintegrating sublingual tablets
b. Place under tongue and let dissolve. Do not swallow chew break or crush. Do not eat
or drink for 10 minutes after taking this drug.
Know and describe the top atypical antipsychotic with greatest incidence of prolonged
QTc interval. - ANS-a. Ziprasidone
Know which antipsychotics have specific instructions for minimum food intake or diet
restrictions. - ANS-a. Avoid with MAOI: Dried, aged, smoked, fermented, spoiled, or
improperly stored meat, fish, poultry, broad bean pods , aged cheeses , tap and
unpasteurized beer , marmite, sauerkraut, kimchee ,soy products/tofu ,banana peel
,tyramine-containing nutritional supplement
b. ziprasidone should be taken with meals of at least 500 calories for optimal and
consistent bioavailability.
c. Lurasidone needs to be taken with 350 kcal
Know an alternative atypical antipsychotic for a patient who has developed diabetes and
has a significant weight gain from treatment with olanzapine. - ANS-a. Quetiapine,
Risperidone, paloperidone (medium risk of weight gain)
b. Asenapine, Amisulpride, Aripiprazole, Lurasidone, Haloperidol, Ziprasidone (low risk
of weight gain)
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this week's
granulocyte count is less than 500mm3. What is the most appropriate recommendation
for drug therapy? - ANS-a. Agranulocytosis (STOP TX)
i. Daily ANC until > or equal to 1000 mm3. When ANC is >1500 mm3, check weekly for
4 weeks and then return to previous monitoring schedule.
Know the common effects of smoking along with antipsychotic drug therapy such as
olanzapine. - ANS-a. olanzapine who smoke tobacco products have decreased serum
concentrations of the medication because of increased drug clearance b. Smoking is
, considered an inducer
Be able to describe three positive symptoms and three negative symptoms of
schizophrenia. - ANS-a. Positive: auditory hallucinations, delusions, repetitive
movements, disorganized speech and behavior
b. Negative: anhedonia, ambivalence, lack of motivation(avolition), alogia, flat affect
Know what a painful muscle spasm with neck muscles pulling a patient's head to the
side called. - ANS-a. Cervical (acute) dystonia
i. Name a common drug therapy to relieve this symptom.
1. Anticholinergic drug such as diphenhydramine (Benadryl) or benztropine (Cogentin).
Know the role of buspirone in the treatment of anxiety and the recommended dose and
time for onset of action. - ANS-a. Buspirone (buspar) is a serotonin partial agonist. NO
gaba involvement.
i. Takes a while to work 2-4 wk. 10-15 mg daily in 2-3 divided doses.
Know what medication an option for patients may be noncompliant on antipsychotics
resulting in multiple hospital stays. - ANS-a. Intramuscular depot (LAI- long acting
injectible)
i. Haloperidol
ii. Flupenazine
iii. Olanazipine
iv. Paliperidone
v. Risperidone*
vi. Aripiprazole*
Know baseline labs and vital measurements tests for the patient who will be prescribed
an antipsychotic such as quetiapine (Seroquel). - ANS-a. Quetiapine- glucose, lipids,
BMI, BP
Describe common side effects/disadvantages of antihistamines. - ANS-a.
Insomnia-sedating effect
b. Decrease stomach acid
c. Blocks allergies
Identify 3-4 disorders/situations when benzodiazepines may be indicated. - ANS-a.
Anxiety
b. Induce sleep/sedation
c. Withdrawal
Verified
Know the route of administration for newer agent asenapine (Saphris) and what
instructions should be given to the patient regarding administration. - ANS-a. Orally
disintegrating sublingual tablets
b. Place under tongue and let dissolve. Do not swallow chew break or crush. Do not eat
or drink for 10 minutes after taking this drug.
Know and describe the top atypical antipsychotic with greatest incidence of prolonged
QTc interval. - ANS-a. Ziprasidone
Know which antipsychotics have specific instructions for minimum food intake or diet
restrictions. - ANS-a. Avoid with MAOI: Dried, aged, smoked, fermented, spoiled, or
improperly stored meat, fish, poultry, broad bean pods , aged cheeses , tap and
unpasteurized beer , marmite, sauerkraut, kimchee ,soy products/tofu ,banana peel
,tyramine-containing nutritional supplement
b. ziprasidone should be taken with meals of at least 500 calories for optimal and
consistent bioavailability.
c. Lurasidone needs to be taken with 350 kcal
Know an alternative atypical antipsychotic for a patient who has developed diabetes and
has a significant weight gain from treatment with olanzapine. - ANS-a. Quetiapine,
Risperidone, paloperidone (medium risk of weight gain)
b. Asenapine, Amisulpride, Aripiprazole, Lurasidone, Haloperidol, Ziprasidone (low risk
of weight gain)
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this week's
granulocyte count is less than 500mm3. What is the most appropriate recommendation
for drug therapy? - ANS-a. Agranulocytosis (STOP TX)
i. Daily ANC until > or equal to 1000 mm3. When ANC is >1500 mm3, check weekly for
4 weeks and then return to previous monitoring schedule.
Know the common effects of smoking along with antipsychotic drug therapy such as
olanzapine. - ANS-a. olanzapine who smoke tobacco products have decreased serum
concentrations of the medication because of increased drug clearance b. Smoking is
, considered an inducer
Be able to describe three positive symptoms and three negative symptoms of
schizophrenia. - ANS-a. Positive: auditory hallucinations, delusions, repetitive
movements, disorganized speech and behavior
b. Negative: anhedonia, ambivalence, lack of motivation(avolition), alogia, flat affect
Know what a painful muscle spasm with neck muscles pulling a patient's head to the
side called. - ANS-a. Cervical (acute) dystonia
i. Name a common drug therapy to relieve this symptom.
1. Anticholinergic drug such as diphenhydramine (Benadryl) or benztropine (Cogentin).
Know the role of buspirone in the treatment of anxiety and the recommended dose and
time for onset of action. - ANS-a. Buspirone (buspar) is a serotonin partial agonist. NO
gaba involvement.
i. Takes a while to work 2-4 wk. 10-15 mg daily in 2-3 divided doses.
Know what medication an option for patients may be noncompliant on antipsychotics
resulting in multiple hospital stays. - ANS-a. Intramuscular depot (LAI- long acting
injectible)
i. Haloperidol
ii. Flupenazine
iii. Olanazipine
iv. Paliperidone
v. Risperidone*
vi. Aripiprazole*
Know baseline labs and vital measurements tests for the patient who will be prescribed
an antipsychotic such as quetiapine (Seroquel). - ANS-a. Quetiapine- glucose, lipids,
BMI, BP
Describe common side effects/disadvantages of antihistamines. - ANS-a.
Insomnia-sedating effect
b. Decrease stomach acid
c. Blocks allergies
Identify 3-4 disorders/situations when benzodiazepines may be indicated. - ANS-a.
Anxiety
b. Induce sleep/sedation
c. Withdrawal
