Multiple Myeloma Exam With Questions And
Answers
Multiple Myeloma is which of the following?
A- incurrable
B-usually occurs in older pop
C-Dx by bone marrow bx
D- All of the above
D- All of the above
T?F Multiple Myeloma can prsent as pathological fx
True
What is considered a medical emergency in Multiple Myeloma?
Cord compression
What is a Multiple Myeloma?
Bone marrow malignancy
is Multiple Myeloma a B cell or T cell Cancer?
B cell
Multiple Myeloma is characterized by the prolferation of maligant _____ cells
Plasma cells
What is the role of a plasma cell?
Secrete antibodies
Malignant plasma cells have abnormally large amounts of what type of immuoglobulin?
IgG
Multiple Myeloma pathogenesis can come from what 3 things? (in genes)
My TIM
1- Tranlocations
2- Inactivation of tumor supressor gene
3- Mutation (oncogene mutation)
After your marrow makes Multiple Myeloma cells where does it go?
Blood stream-->
Nodes--> (more made)
Soft tissue-->
Plasmacytoma (maligancy growing on soft tissue)
What happens to immunoglobulin profuction and antibody production?
-Immunoglobulin is abnormal
-Antibody prodcution is ineffective
, abnormal immunoglobulins and antibodies cause damage to what two organs?
1-Kidney
2-bone
T/F Multiple Myeloma effects all races and geography
True
What race is at higher risk?
blacks
what is the medan dx age of Multiple Myeloma?
A) 50
B)60
C)70
D)20
70
What have they found as a possible risk factor?
Radiation (atomic bomb surviers)
T/F Multiple Myeloma is the most common blood cacner?
False; second
What is the presentation of multiple myeloma?
SWAP CRIBz
S- Spinal cord compression
W-Weight loss
A-Anemia
P-Pathologic fracture
C-HyperCalcemia
R-renal damage
I-Indicdental find
B-bone pain
Z-ZZZZ (tired)
what is a manifestation of multiple myeloma that can be seen visually on inspection
extramedullary plasmacytoma
What two tests would you do during work up? (excluding labs)
-Skeletal survery (HEAD TO TOE XRAY)
-Bone marrow bx
What labs are you going to get on your multiple myeloma pateint?
Answers
Multiple Myeloma is which of the following?
A- incurrable
B-usually occurs in older pop
C-Dx by bone marrow bx
D- All of the above
D- All of the above
T?F Multiple Myeloma can prsent as pathological fx
True
What is considered a medical emergency in Multiple Myeloma?
Cord compression
What is a Multiple Myeloma?
Bone marrow malignancy
is Multiple Myeloma a B cell or T cell Cancer?
B cell
Multiple Myeloma is characterized by the prolferation of maligant _____ cells
Plasma cells
What is the role of a plasma cell?
Secrete antibodies
Malignant plasma cells have abnormally large amounts of what type of immuoglobulin?
IgG
Multiple Myeloma pathogenesis can come from what 3 things? (in genes)
My TIM
1- Tranlocations
2- Inactivation of tumor supressor gene
3- Mutation (oncogene mutation)
After your marrow makes Multiple Myeloma cells where does it go?
Blood stream-->
Nodes--> (more made)
Soft tissue-->
Plasmacytoma (maligancy growing on soft tissue)
What happens to immunoglobulin profuction and antibody production?
-Immunoglobulin is abnormal
-Antibody prodcution is ineffective
, abnormal immunoglobulins and antibodies cause damage to what two organs?
1-Kidney
2-bone
T/F Multiple Myeloma effects all races and geography
True
What race is at higher risk?
blacks
what is the medan dx age of Multiple Myeloma?
A) 50
B)60
C)70
D)20
70
What have they found as a possible risk factor?
Radiation (atomic bomb surviers)
T/F Multiple Myeloma is the most common blood cacner?
False; second
What is the presentation of multiple myeloma?
SWAP CRIBz
S- Spinal cord compression
W-Weight loss
A-Anemia
P-Pathologic fracture
C-HyperCalcemia
R-renal damage
I-Indicdental find
B-bone pain
Z-ZZZZ (tired)
what is a manifestation of multiple myeloma that can be seen visually on inspection
extramedullary plasmacytoma
What two tests would you do during work up? (excluding labs)
-Skeletal survery (HEAD TO TOE XRAY)
-Bone marrow bx
What labs are you going to get on your multiple myeloma pateint?
