PATHOPHYSIOLOGY MID-TERM STUDY GUIDE
1. Which patient is the universal blood donor (anyone can receive their blood type)?
A) AB negative
B) AB positive
C) O negative
D) O positive: C) O negative
2. Hyperbilirubinemia in infants is caused by two things, what are they?
A) Rh positive father and Rh negative mother
B) Liver immaturity and breakdown of blood (hemolysis) at birth
C) Prematurity and a small liver at birth
D) Bilirubin conjugation and digestion: B) Liver immaturity and breakdown of blood
(hemolysis) at birth
D) Bilirubin conjugation and digestion
3. Transfusions of may correct a clotting
factor defi- ciency.
A) red blood cells
B) platelets
C) albumin
D) iron: B) platelets
4. T
he precursor or parent cells of thrombocytes are called .
A) megakaryocytes
B) blast cells
C) band cells
D) reticulocytes: A) megakaryocytes
5. A nurse practitioner is providing care for a patient with low levels of the plasma protein
(gamma globulin). The nurse would recognize that the patient is at risk for developing which of
the following health problems?
A) Anemia
B) Jaundice
C) Blood clots
D) Infections: D) Infections
6. The formation of
all blood cells is called .
, PATHOPHYSIOLOGY MID-TERM STUDY GUIDE
A) Erythropoietin
B) Angiogenesis
C) Hematopoiesis
D) Erythrogenesis: C) Hematopoiesis
7. Which medical diagnosis correlates with a blood sample showing an ex- cessive
hematocrit or abnormally high number of red blood cells due to dehydration, hypoxia or a
bone marrow disorder?
A) Polycythemia
B) Thalassemia
C) Chromocytosis
D) Thrombocytosis: A) Polycythemia
8. Megaloblastic or pernicious anemia is caused by a lack of:
A) clotting factors
B) B2 and/or Iron
C) B12 and/or Folic Acid
D) Protein and vitamin C: C) B12 and/or Folic Acid
9. Infectious mononucleosis is an infection usually caused by
. In young adults, the disease often results in fever, sore throat, enlarged
lymph nodes in the neck; the liver or spleen may also become swollen. Treatment usually includes
drinking enough fluids, getting sufficient rest, and taking pain medications such as
acetaminophen and ibuprofen.
Symptoms may last for months.
A) Toxoplasmosis
B) Epstein-Barr Virus (EBV)
C) Non-Hodgkin's Lymphoma
D) Cytomegalovirus: B) Epstein-Barr Virus (EBV)
10. An abnormally low number of neutrophils which can place
a patient at risk for infection is called .
A) Kostmann Syndrome
B) Non-Hodgkins Lymphoma
C) Leukopoiesis
D) Neutropenia: D) Neutropenia
11. A couple who are expecting their first child has been advised by friends to consider
harvesting umbilical cord blood in order to have a future source of stem cells. Why are stem cells
so valuable?
, PATHOPHYSIOLOGY MID-TERM STUDY GUIDE
A) Stem cells can be used to regenerate damaged organs should the need ever arise.
B) Stem cells can help treat some cancers and anemias, but they must come from your child
himself or herself.
C) Stem cells can be used as a source of reserve cells for the entire blood production system.
D) Stem cells can help correct autoimmune diseases and some congenital defects.: C) Stem cells
can be used as a source of reserve cells for the entire blood production system.
12. How long do normal red blood cells live before they are recycled by the body?
A) 200 days
B) 120 days
C) 12 days
D) 1200 days: B) 120 days
13. A common cause of
neutropenia is .
A) hypoxemia
B) chemotherapy
C) infection
D) ischemia: B) chemotherapy
14. If a male patient is dehydrated, the blood from his lab draw will most likely be:
A) hemo-diluted.
B) undifferentiated.
C) unchanged.
D) hemo-concentrated.: D) hemo-concentrated.
15. A patient in the hospital needs a blood transfusion. The patient is AB- but there is no AB-
blood stored in the hospital's blood bank. This patient can receive all of the following blood types
EXCEPT:
A) A-
B) A+
C) B-
D) O-: B) A+
1. Which patient is the universal blood donor (anyone can receive their blood type)?
A) AB negative
B) AB positive
C) O negative
D) O positive: C) O negative
2. Hyperbilirubinemia in infants is caused by two things, what are they?
A) Rh positive father and Rh negative mother
B) Liver immaturity and breakdown of blood (hemolysis) at birth
C) Prematurity and a small liver at birth
D) Bilirubin conjugation and digestion: B) Liver immaturity and breakdown of blood
(hemolysis) at birth
D) Bilirubin conjugation and digestion
3. Transfusions of may correct a clotting
factor defi- ciency.
A) red blood cells
B) platelets
C) albumin
D) iron: B) platelets
4. T
he precursor or parent cells of thrombocytes are called .
A) megakaryocytes
B) blast cells
C) band cells
D) reticulocytes: A) megakaryocytes
5. A nurse practitioner is providing care for a patient with low levels of the plasma protein
(gamma globulin). The nurse would recognize that the patient is at risk for developing which of
the following health problems?
A) Anemia
B) Jaundice
C) Blood clots
D) Infections: D) Infections
6. The formation of
all blood cells is called .
, PATHOPHYSIOLOGY MID-TERM STUDY GUIDE
A) Erythropoietin
B) Angiogenesis
C) Hematopoiesis
D) Erythrogenesis: C) Hematopoiesis
7. Which medical diagnosis correlates with a blood sample showing an ex- cessive
hematocrit or abnormally high number of red blood cells due to dehydration, hypoxia or a
bone marrow disorder?
A) Polycythemia
B) Thalassemia
C) Chromocytosis
D) Thrombocytosis: A) Polycythemia
8. Megaloblastic or pernicious anemia is caused by a lack of:
A) clotting factors
B) B2 and/or Iron
C) B12 and/or Folic Acid
D) Protein and vitamin C: C) B12 and/or Folic Acid
9. Infectious mononucleosis is an infection usually caused by
. In young adults, the disease often results in fever, sore throat, enlarged
lymph nodes in the neck; the liver or spleen may also become swollen. Treatment usually includes
drinking enough fluids, getting sufficient rest, and taking pain medications such as
acetaminophen and ibuprofen.
Symptoms may last for months.
A) Toxoplasmosis
B) Epstein-Barr Virus (EBV)
C) Non-Hodgkin's Lymphoma
D) Cytomegalovirus: B) Epstein-Barr Virus (EBV)
10. An abnormally low number of neutrophils which can place
a patient at risk for infection is called .
A) Kostmann Syndrome
B) Non-Hodgkins Lymphoma
C) Leukopoiesis
D) Neutropenia: D) Neutropenia
11. A couple who are expecting their first child has been advised by friends to consider
harvesting umbilical cord blood in order to have a future source of stem cells. Why are stem cells
so valuable?
, PATHOPHYSIOLOGY MID-TERM STUDY GUIDE
A) Stem cells can be used to regenerate damaged organs should the need ever arise.
B) Stem cells can help treat some cancers and anemias, but they must come from your child
himself or herself.
C) Stem cells can be used as a source of reserve cells for the entire blood production system.
D) Stem cells can help correct autoimmune diseases and some congenital defects.: C) Stem cells
can be used as a source of reserve cells for the entire blood production system.
12. How long do normal red blood cells live before they are recycled by the body?
A) 200 days
B) 120 days
C) 12 days
D) 1200 days: B) 120 days
13. A common cause of
neutropenia is .
A) hypoxemia
B) chemotherapy
C) infection
D) ischemia: B) chemotherapy
14. If a male patient is dehydrated, the blood from his lab draw will most likely be:
A) hemo-diluted.
B) undifferentiated.
C) unchanged.
D) hemo-concentrated.: D) hemo-concentrated.
15. A patient in the hospital needs a blood transfusion. The patient is AB- but there is no AB-
blood stored in the hospital's blood bank. This patient can receive all of the following blood types
EXCEPT:
A) A-
B) A+
C) B-
D) O-: B) A+
